ID   TM2D3_XENTR             Reviewed;         247 AA.
AC   Q07FZ2;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=TM2 domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=tm2d3; ORFNames=TGas058n18.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TM2 family. {ECO:0000305}.
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DR   EMBL; CR942406; CAL49417.1; -; mRNA.
DR   AlphaFoldDB; Q07FZ2; -.
DR   STRING; 8364.ENSXETP00000055979; -.
DR   PaxDb; Q07FZ2; -.
DR   eggNOG; KOG4272; Eukaryota.
DR   InParanoid; Q07FZ2; -.
DR   Proteomes; UP000008143; Genome assembly.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF05154; TM2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..247
FT                   /note="TM2 domain-containing protein 3"
FT                   /id="PRO_0000298993"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        87
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        99
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        139
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        155
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        169
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   247 AA;  27464 MW;  2B1378BF8093A854 CRC64;
     MIPMMTLKRV CRVLLFITQM YVLSGRGFLS FEYSEPVAQP LKDHFPSSTI ATSTKATATK
     IPDYMEKCPS NGQCSRLPSD CMTCATNYSC IYGKPVTFNC TAKNGVVCFD VNSQPQEYFT
     ISMTCQFCWQ LPPSDYVCNL SSSCKTVSCP RQRYNTTCTV LDHAHCLGNR TFPKMLYCNW
     TGGYKWSTAL ALSITLGGFG ADRFYLGQWR EGLGKLFSFG GLGIWTLIDV FLISVGYVGP
     ADGSLYI