ID   TM39B_DANRE             Reviewed;         491 AA.
AC   Q7ZW11;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Transmembrane protein 39B;
GN   Name=tmem39b; ORFNames=zgc:55419;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM39 family. {ECO:0000305}.
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DR   EMBL; BC045334; AAH45334.1; -; mRNA.
DR   RefSeq; NP_956154.1; NM_199860.1.
DR   AlphaFoldDB; Q7ZW11; -.
DR   STRING; 7955.ENSDARP00000006893; -.
DR   PaxDb; Q7ZW11; -.
DR   Ensembl; ENSDART00000002095; ENSDARP00000006893; ENSDARG00000018956.
DR   GeneID; 334110; -.
DR   KEGG; dre:334110; -.
DR   CTD; 55116; -.
DR   ZFIN; ZDB-GENE-030131-6042; tmem39b.
DR   eggNOG; KOG3828; Eukaryota.
DR   GeneTree; ENSGT00390000018895; -.
DR   HOGENOM; CLU_028992_0_0_1; -.
DR   InParanoid; Q7ZW11; -.
DR   OMA; IEWHFVL; -.
DR   OrthoDB; 1460710at2759; -.
DR   PhylomeDB; Q7ZW11; -.
DR   TreeFam; TF321110; -.
DR   PRO; PR:Q7ZW11; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 13.
DR   Bgee; ENSDARG00000018956; Expressed in mature ovarian follicle and 25 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   InterPro; IPR019397; Uncharacterised_TMEM39.
DR   PANTHER; PTHR12995; PTHR12995; 1.
DR   Pfam; PF10271; Tmp39; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..491
FT                   /note="Transmembrane protein 39B"
FT                   /id="PRO_0000279235"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        449..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        9
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        20
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        29
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        45
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   491 AA;  55776 MW;  341367B966576644 CRC64;
     MAGGRRGANR TTYCRSPLSN DTGSVGNGNH STSSPVTGVR SRTRNGSGTG MSSPPLATQT
     VVPLKHCKIP ELSMDKNVLF ELHLFACHLI ALFVHYVNIY KTVWWYPPSH PPSHTSLNFH
     LIDYNMLVFT VIVLARRLIA AIVKEASQSG KLSFPHSVFL VTARFAVLTL AGWSLCRSLI
     YLFKTYSVLS LLFLCYPFGM YIPFFRLSCD FRRAGSMSPL SGIGSKDVGA AALGRGGRDY
     LSVLKETWKQ HTSQLYSAQP MPTHACCLSP DLIRKEVEYL KMDFNWRMKE VLVSSMLSAY
     YVAFVPVWFV KSTQYVDKRW SCELFILVSV STSVILMRHL LPPRYCDLLH KAAAHLGCWQ
     KVDPSLCSNV LQHIWTEEYM WPQGVLVKHS KNVYKAMGHY NVAVPSDVSH YRFYFFFNKP
     LRILNILIIL EGAMIFYQLY SLMCSEKWHQ TISLALILFS NYYAFFKLLR DRIVLGKAYS
     YSASASNQKV S