ID   AC4_TLCVA               Reviewed;         102 AA.
AC   P36283;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   02-JUN-2021, entry version 55.
DE   RecName: Full=Protein C4;
DE   AltName: Full=10.9 kDa protein;
DE   AltName: Full=Protein L4;
GN   ORFNames=C4, L4;
OS   Tomato leaf curl virus (strain Australia) (ToLCV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=223353;
OH   NCBI_TaxID=185024; Cynanchum acutum.
OH   NCBI_TaxID=145753; Malva parviflora (Little mallow) (Cheeseweed mallow).
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8423446; DOI=10.1099/0022-1317-74-1-147;
RA   Dry I.B., Rigden J.E., Krake L.R., Mullineaux P.M., Rezaian M.A.;
RT   "Nucleotide sequence and genome organization of tomato leaf curl
RT   geminivirus.";
RL   J. Gen. Virol. 74:147-151(1993).
RN   [2]
RP   FUNCTION.
RX   PubMed=7941358; DOI=10.1006/viro.1994.1606;
RA   Rigden J.E., Krake L.R., Rezaian M.A., Dry I.B.;
RT   "ORF C4 of tomato leaf curl geminivirus is a determinant of symptom
RT   severity.";
RL   Virology 204:847-850(1994).
CC   -!- FUNCTION: Pathogenicity determinant. May act as a suppressor of RNA-
CC       mediated gene silencing, also known as post-transcriptional gene
CC       silencing (PTGS), a mechanism of plant viral defense that limits the
CC       accumulation of viral RNAs. {ECO:0000269|PubMed:7941358}.
CC   -!- SIMILARITY: Belongs to the geminiviridae protein AC4/C4 family.
CC       {ECO:0000305}.
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DR   EMBL; S53251; AAM33782.1; -; Genomic_DNA.
DR   PIR; JQ1890; JQ1890.
DR   RefSeq; NP_632007.1; NC_003896.1.
DR   SMR; P36283; -.
DR   GeneID; 944505; -.
DR   KEGG; vg:944505; -.
DR   Proteomes; UP000008246; Genome.
DR   InterPro; IPR002488; Gemini_C4.
DR   Pfam; PF01492; Gemini_C4; 1.
PE   3: Inferred from homology;
KW   Suppressor of RNA silencing.
FT   CHAIN           1..102
FT                   /note="Protein C4"
FT                   /id="PRO_0000222296"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          47..86
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   102 AA;  11410 MW;  B4671A2886B8CD08 CRC64;
     MRMGSLISTC LSSSKASSSA RINDSSTWSP PPGQHISIRT FRELRARQTS SPIWRRTETP
     SNGESFRSMD DLQEGDNNQP MTLTPRRLTL EVSQRLLTSL GN