ID   TM45B_BOVIN             Reviewed;         276 AA.
AC   Q3T130;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Transmembrane protein 45B;
GN   Name=TMEM45B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM45 family. {ECO:0000305}.
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DR   EMBL; BC102148; AAI02149.1; -; mRNA.
DR   RefSeq; NP_001029547.1; NM_001034375.2.
DR   RefSeq; XP_005226905.1; XM_005226848.3.
DR   AlphaFoldDB; Q3T130; -.
DR   SMR; Q3T130; -.
DR   STRING; 9913.ENSBTAP00000023404; -.
DR   PaxDb; Q3T130; -.
DR   Ensembl; ENSBTAT00000023404; ENSBTAP00000023404; ENSBTAG00000017602.
DR   Ensembl; ENSBTAT00000068073; ENSBTAP00000063813; ENSBTAG00000017602.
DR   Ensembl; ENSBTAT00000068863; ENSBTAP00000072207; ENSBTAG00000017602.
DR   Ensembl; ENSBTAT00000080460; ENSBTAP00000073149; ENSBTAG00000017602.
DR   GeneID; 510305; -.
DR   KEGG; bta:510305; -.
DR   CTD; 120224; -.
DR   VEuPathDB; HostDB:ENSBTAG00000017602; -.
DR   VGNC; VGNC:36089; TMEM45B.
DR   eggNOG; ENOG502QU0J; Eukaryota.
DR   GeneTree; ENSGT00940000157181; -.
DR   HOGENOM; CLU_059568_0_0_1; -.
DR   InParanoid; Q3T130; -.
DR   OMA; FGAPEWD; -.
DR   OrthoDB; 1297629at2759; -.
DR   TreeFam; TF328673; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000017602; Expressed in rumen papilla and 59 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006904; DUF716.
DR   InterPro; IPR042127; TMEM45.
DR   PANTHER; PTHR16007; PTHR16007; 1.
DR   Pfam; PF04819; DUF716; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..276
FT                   /note="Transmembrane protein 45B"
FT                   /id="PRO_0000271198"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         271
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q497B2"
FT   MOD_RES         273
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8VCZ2"
SQ   SEQUENCE   276 AA;  32206 MW;  8494A1E716524417 CRC64;
     MANFKGHALP GSFFLIVGLW WSLKYPLKYF YQKEKSNQLT HHYQRLEIIE AAIRTLFAVI
     GILVEQFVPD GPHLHLYHED HWVKLMNWQH STMYLFFAVS GIMDMLTYLI THVPLGLDRL
     VMALAAFNEG FLFYYHVRDR PPLDQHIHSL LLYTVFGGAL SLAVEVVLRD NIVLELFRTS
     LLLLQGTWFW QIGFVLFPPF GGPEWDQNSH DNIMFVTMCF CWHYLAALCI LAASYSLVYC
     FLTRVKRPED REVIGIQKLR SDHTYRKALL SGSDEE