ID   TM45B_DANRE             Reviewed;         283 AA.
AC   Q6P0S3;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Transmembrane protein 45B;
GN   Name=tmem45b; ORFNames=zgc:77892;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM45 family. {ECO:0000305}.
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DR   EMBL; BC065467; AAH65467.1; -; mRNA.
DR   RefSeq; NP_991240.1; NM_205677.1.
DR   AlphaFoldDB; Q6P0S3; -.
DR   SMR; Q6P0S3; -.
DR   STRING; 7955.ENSDARP00000100942; -.
DR   PaxDb; Q6P0S3; -.
DR   PRIDE; Q6P0S3; -.
DR   GeneID; 402977; -.
DR   KEGG; dre:402977; -.
DR   CTD; 120224; -.
DR   ZFIN; ZDB-GENE-040426-1904; tmem45b.
DR   eggNOG; ENOG502QU0J; Eukaryota.
DR   InParanoid; Q6P0S3; -.
DR   OrthoDB; 1297629at2759; -.
DR   PhylomeDB; Q6P0S3; -.
DR   PRO; PR:Q6P0S3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006904; DUF716.
DR   InterPro; IPR042127; TMEM45.
DR   PANTHER; PTHR16007; PTHR16007; 1.
DR   Pfam; PF04819; DUF716; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..283
FT                   /note="Transmembrane protein 45B"
FT                   /id="PRO_0000271202"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          261..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  32760 MW;  1EE0B314EF00DF10 CRC64;
     MANFKGHALP GTFFLLFGLW WSIKCPFRQI LRRKERQVGD RERQKLTALF NRIDLIEGSL
     KIFFAFVGIM AEQFVPDGPH AHLYQDGWVK LMNWQHSTMY LFYGISGIAD VLSVSSHHVP
     VGLDRLFLSL ALFVEGFLFY FHIHNREPLD QHIHSLLLFA VFGGSASTMM EVFKRENAVL
     ELLRCTLAIL QGTWFYQIGF VLYPLSGPEW DLTRHDNIMF ITMCFCWHLA VALLIVGICY
     CGVFWTSKWC ERRQRGDMEM GLRKSTSTDS SSQKALLQES DEE