ID   TM45B_XENLA             Reviewed;         280 AA.
AC   Q6NS09;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Transmembrane protein 45B;
GN   Name=tmem45b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM45 family. {ECO:0000305}.
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DR   EMBL; BC070544; AAH70544.1; -; mRNA.
DR   RefSeq; NP_001084845.1; NM_001091376.1.
DR   AlphaFoldDB; Q6NS09; -.
DR   SMR; Q6NS09; -.
DR   DNASU; 431891; -.
DR   GeneID; 431891; -.
DR   KEGG; xla:431891; -.
DR   CTD; 431891; -.
DR   Xenbase; XB-GENE-17333294; tmem45b.S.
DR   Proteomes; UP000186698; Chromosome 7S.
DR   Bgee; 431891; Expressed in zone of skin and 14 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006904; DUF716.
DR   InterPro; IPR042127; TMEM45.
DR   PANTHER; PTHR16007; PTHR16007; 1.
DR   Pfam; PF04819; DUF716; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..280
FT                   /note="Transmembrane protein 45B"
FT                   /id="PRO_0000271203"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   280 AA;  32002 MW;  B662044B7E3B95DB CRC64;
     MANFKGHALP GSFFLVFGLW WSVKYPLRYL NSKVKGNCRS NKCYDRLELI EGILKALFSL
     IGILAEQFVP DGPHMHLVNG EDHSWVKLMN WQHTTMYLFY GISGVVDILT YFPLNLPRGL
     DRLSLGIAVI VEGLLFYYHV HNRPALDQHI HSLLLIAVFG CAISIMIEVF MRNDIVLELF
     RASLSILQGT WFWQIGFVLY PLGGAPEWNQ TDHDNVMFIT MCFCWHYAVA LLIMAINYSL
     VYYCVNRHKK LPVIVDNGLI KINSKKAEVE ASLLAGSDEE