TM50B_PAPAN
ID TM50B_PAPAN Reviewed; 158 AA.
AC A9CAZ8;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 39.
DE RecName: Full=Transmembrane protein 50B;
GN Name=TMEM50B;
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC comparative sequencing initiative.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: May form homotrimers or homodimers.
CC {ECO:0000250|UniProtKB:Q9D1X9}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:Q9D1X9}; Multi-pass membrane protein
CC {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9D1X9};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the UPF0220 family. {ECO:0000305}.
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DR EMBL; DP000484; ABW97194.1; -; Genomic_DNA.
DR RefSeq; NP_001162256.1; NM_001168785.1.
DR AlphaFoldDB; A9CAZ8; -.
DR STRING; 9555.ENSPANP00000016716; -.
DR Ensembl; ENSPANT00000018361; ENSPANP00000016716; ENSPANG00000018699.
DR GeneID; 100137247; -.
DR KEGG; panu:100137247; -.
DR CTD; 757; -.
DR eggNOG; KOG3393; Eukaryota.
DR GeneTree; ENSGT00940000155131; -.
DR OrthoDB; 1422977at2759; -.
DR Proteomes; UP000028761; Chromosome 4.
DR Bgee; ENSPANG00000018699; Expressed in thyroid gland and 66 other tissues.
DR ExpressionAtlas; A9CAZ8; baseline.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007919; UPF0220.
DR PANTHER; PTHR13180; PTHR13180; 1.
DR Pfam; PF05255; UPF0220; 1.
PE 3: Inferred from homology;
KW Acetylation; Endoplasmic reticulum; Golgi apparatus; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:P56557"
FT CHAIN 2..158
FT /note="Transmembrane protein 50B"
FT /id="PRO_0000328500"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:P56557"
SQ SEQUENCE 158 AA; 17936 MW; 515ABB6AAA817DEB CRC64;
MAGFLDNFRW PECECIDWSE RRNAVASVVA GILFFTGWWI MIDAAVVYPK PEQLNHAFHT
CGVFSTLAFF MINAVSNAQV RGDSYESGCL GRTGARVWLF IGFMLMFGSL IASMWILFGA
YVTQNTDVYP GLAVFFQNAL IFFSTLIYKF GRTEELWT
