ID   TM52B_MOUSE             Reviewed;         186 AA.
AC   Q0VBF2;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 2.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Transmembrane protein 52B;
DE   Flags: Precursor;
GN   Name=Tmem52b;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
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DR   EMBL; BC120661; AAI20662.2; -; mRNA.
DR   EMBL; BC120663; AAI20664.2; -; mRNA.
DR   CCDS; CCDS39659.1; -.
DR   RefSeq; NP_001074655.1; NM_001081186.1.
DR   AlphaFoldDB; Q0VBF2; -.
DR   STRING; 10090.ENSMUSP00000032263; -.
DR   iPTMnet; Q0VBF2; -.
DR   PhosphoSitePlus; Q0VBF2; -.
DR   PaxDb; Q0VBF2; -.
DR   PRIDE; Q0VBF2; -.
DR   ProteomicsDB; 259231; -.
DR   Antibodypedia; 23262; 50 antibodies from 13 providers.
DR   Ensembl; ENSMUST00000032263; ENSMUSP00000032263; ENSMUSG00000030160.
DR   GeneID; 330428; -.
DR   KEGG; mmu:330428; -.
DR   UCSC; uc009efx.1; mouse.
DR   CTD; 120939; -.
DR   MGI; MGI:2442838; Tmem52b.
DR   VEuPathDB; HostDB:ENSMUSG00000030160; -.
DR   eggNOG; ENOG502S0XU; Eukaryota.
DR   GeneTree; ENSGT00730000111328; -.
DR   HOGENOM; CLU_100623_2_0_1; -.
DR   InParanoid; Q0VBF2; -.
DR   OMA; RLWYIWL; -.
DR   OrthoDB; 1323580at2759; -.
DR   PhylomeDB; Q0VBF2; -.
DR   TreeFam; TF336037; -.
DR   BioGRID-ORCS; 330428; 1 hit in 74 CRISPR screens.
DR   PRO; PR:Q0VBF2; -.
DR   Proteomes; UP000000589; Chromosome 6.
DR   RNAct; Q0VBF2; protein.
DR   Bgee; ENSMUSG00000030160; Expressed in right kidney and 19 other tissues.
DR   ExpressionAtlas; Q0VBF2; baseline and differential.
DR   Genevisible; Q0VBF2; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038942; TMEM52.
DR   PANTHER; PTHR33955; PTHR33955; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..186
FT                   /note="Transmembrane protein 52B"
FT                   /id="PRO_0000294449"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          158..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   186 AA;  20312 MW;  2EA4E0D30C640641 CRC64;
     MFSLMTAWAQ VLMASGLFYF IQLPGARSEE NCVNTEHCLT TDWVHLWYIW LLVVVGALLL
     LCGLTSVCFR CCLSRPENGE DGAPPPYEVT VIAFDHDSTL QSTITSLQSV FGPAARRILA
     VAHAHSSLGQ LPSSVDTLPG YEEALRMSRF TVARCGQKVP DLPSVPEEKQ LPPTGKESPG
     TEPPSH