ID   TM53A_XENLA             Reviewed;         285 AA.
AC   Q5PPS7;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Transmembrane protein 53-A;
GN   Name=tmem53-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM53 family. {ECO:0000305}.
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DR   EMBL; BC087518; AAH87518.1; -; mRNA.
DR   RefSeq; NP_001088819.1; NM_001095350.1.
DR   AlphaFoldDB; Q5PPS7; -.
DR   ESTHER; xenla-tm53a; Duf_829.
DR   DNASU; 496092; -.
DR   GeneID; 496092; -.
DR   KEGG; xla:496092; -.
DR   CTD; 496092; -.
DR   Xenbase; XB-GENE-1018177; tmem53.S.
DR   OMA; FCALWDL; -.
DR   OrthoDB; 916101at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 496092; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR008547; DUF829_TMEM53.
DR   PANTHER; PTHR12265; PTHR12265; 1.
DR   Pfam; PF05705; DUF829; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..285
FT                   /note="Transmembrane protein 53-A"
FT                   /id="PRO_0000284121"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  32940 MW;  C318AB85A6B7F46B CRC64;
     MGDSELDYTI EFPEPSLQGW PWDPEREPVV ILLGWGGCKD HYLAKYSAIY HNQGCTVIKY
     TAAWKAVFIT ESLGLNSLRE DAKKLLELLF DYEIEKSPIV FHVFSNGGFM LYRYIVELLH
     SHCPLNKLHV VGTIFDSAPG NRNVIGSVRA LDTILRTSTN KAFRFLALAA FAILVIILRI
     LLYPLTRFLH ENHYDAMKKD PSRWPQLYLY SRADPIISYL DVESMIAARR RRCLPTETLD
     FGKSEHVSHF RRFPQRYSEI CTSFLRDCVR KASISMLRSE HPVSF