ID   TM53B_XENLA             Reviewed;         285 AA.
AC   Q6DJC8;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Transmembrane protein 53-B;
GN   Name=tmem53-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM53 family. {ECO:0000305}.
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DR   EMBL; BC075254; AAH75254.1; -; mRNA.
DR   RefSeq; NP_001086490.1; NM_001093021.1.
DR   AlphaFoldDB; Q6DJC8; -.
DR   ESTHER; xenla-tm53b; Duf_829.
DR   DNASU; 446324; -.
DR   GeneID; 446324; -.
DR   KEGG; xla:446324; -.
DR   CTD; 446324; -.
DR   Xenbase; XB-GENE-6251497; tmem53.L.
DR   OrthoDB; 916101at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 446324; Expressed in testis and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR008547; DUF829_TMEM53.
DR   PANTHER; PTHR12265; PTHR12265; 1.
DR   Pfam; PF05705; DUF829; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..285
FT                   /note="Transmembrane protein 53-B"
FT                   /id="PRO_0000284122"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  32673 MW;  C25A49E1E4154A5D CRC64;
     MGDPELDYTI EFPEPSLQGC PWDPEREPVV ILLGWGGCKD QYLAKYSAIY HNQGCTVIKY
     TAAWNAVFIS ESLGFSSLRE DAKKLLELLF DYEIEKSPIL FHVFSNGGFM LYRYIVELLH
     SHCRLNKLHV VGTIFDSAPG NRNVIGSVRA LDTILRTSTN NAIRFLALAA FAIMVIILRI
     VLYPVTKFLH ENHYDAMKKD SSRWPQLYLY SRADPIISYI DVESMIAARR RCCLPTEALD
     FGKSEHVSHF RRFPHRYSEM CTSFLRDCVR KAAVSMLTSE HPVSF