ID   TM5_TERAN               Reviewed;          97 AA.
AC   P0DN65;
DT   09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT   09-DEC-2015, sequence version 1.
DT   25-MAY-2022, entry version 10.
DE   RecName: Full=Teretoxin Tan22.5 {ECO:0000303|PubMed:26025559};
DE   Flags: Precursor;
OS   Terebra anilis (Auger snail) (Cinguloterebra anilis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Terebridae; Terebra.
OX   NCBI_TaxID=553697;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=26025559; DOI=10.1093/gbe/evv104;
RA   Gorson J., Ramrattan G., Verdes A., Wright E.M., Kantor Y.,
RA   Rajaram Srinivasan R., Musunuri R., Packer D., Albano G., Qiu W.G.,
RA   Holford M.;
RT   "Molecular diversity and gene evolution of the venom arsenal of Terebridae
RT   predatory marine snails.";
RL   Genome Biol. Evol. 7:1761-1778(2015).
RN   [2]
RP   SUPERFAMILY.
RA   Gorson J., Anand P., Holford M.;
RL   Unpublished observations (OCT-2015).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:26025559}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:26025559}.
CC   -!- DOMAIN: The cysteine framework is XXII (C-C-C-C-C-C-C-C).
CC   -!- PTM: Contains 4 disulfide bonds. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the teretoxin J (TJ) superfamily.
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DR   AlphaFoldDB; P0DN65; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   PROPEP          22..59
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000435096"
FT   CHAIN           60..97
FT                   /note="Teretoxin Tan22.5"
FT                   /id="PRO_0000435097"
SQ   SEQUENCE   97 AA;  10763 MW;  B8A1C912EE3CE197 CRC64;
     MGKFTVTLLV FLMVLPLIVL PARDEEHDEK DKRSAAQAIP RYSSKPGESL IDLMARNQKS
     SGNEACQDSD CDKDCGDCFC GYFKPTCSCH CLDMIPL