ID   TM88B_BOVIN             Reviewed;         166 AA.
AC   Q0VD38;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Transmembrane protein 88B;
GN   Name=TMEM88B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM88 family. {ECO:0000305}.
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DR   EMBL; BC119848; AAI19849.1; -; mRNA.
DR   RefSeq; NP_001070426.1; NM_001076958.1.
DR   AlphaFoldDB; Q0VD38; -.
DR   STRING; 9913.ENSBTAP00000042400; -.
DR   PaxDb; Q0VD38; -.
DR   Ensembl; ENSBTAT00000044963; ENSBTAP00000042400; ENSBTAG00000023784.
DR   GeneID; 767837; -.
DR   KEGG; bta:767837; -.
DR   CTD; 643965; -.
DR   VEuPathDB; HostDB:ENSBTAG00000023784; -.
DR   VGNC; VGNC:36121; TMEM88B.
DR   eggNOG; ENOG502RYZS; Eukaryota.
DR   GeneTree; ENSGT00730000111599; -.
DR   HOGENOM; CLU_1602208_0_0_1; -.
DR   InParanoid; Q0VD38; -.
DR   OMA; EQLCAWV; -.
DR   OrthoDB; 1609820at2759; -.
DR   TreeFam; TF332743; -.
DR   Proteomes; UP000009136; Chromosome 16.
DR   Bgee; ENSBTAG00000023784; Expressed in midbrain and 64 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:GO_Central.
DR   InterPro; IPR033355; TMEM88.
DR   PANTHER; PTHR28628; PTHR28628; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..166
FT                   /note="Transmembrane protein 88B"
FT                   /id="PRO_0000346445"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   166 AA;  17853 MW;  DEE2040BB2994500 CRC64;
     MSDQERETEE DEGGDPSDTA PMLPQRLPDH QASDLMSPGW ASLAARGLGT LLFQGWALAR
     LLLHLLLPAA VFLLVLLPAA AVVYLGFLCH SRVHPAPRPA CRALLSDRGS AAVIVLGFLS
     LPPLLVLASA ARARLARRLH SLLPPPTWSP GPHRQSDGEK QLCAWV