TMA10_YEAST
ID TMA10_YEAST Reviewed; 86 AA.
AC Q06177; D6VYW9;
DT 24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Translation machinery-associated protein 10;
GN Name=TMA10; OrderedLocusNames=YLR327C; ORFNames=L8543.1;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-79, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28 AND SER-79, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- MISCELLANEOUS: Present with 504 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the STF2 family. {ECO:0000305}.
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DR EMBL; U20618; AAB64510.1; -; Genomic_DNA.
DR EMBL; BK006945; DAA09635.1; -; Genomic_DNA.
DR PIR; S53404; S53404.
DR RefSeq; NP_013431.1; NM_001182216.1.
DR AlphaFoldDB; Q06177; -.
DR BioGRID; 31590; 60.
DR DIP; DIP-2138N; -.
DR IntAct; Q06177; 1.
DR MINT; Q06177; -.
DR STRING; 4932.YLR327C; -.
DR iPTMnet; Q06177; -.
DR MaxQB; Q06177; -.
DR PaxDb; Q06177; -.
DR PRIDE; Q06177; -.
DR EnsemblFungi; YLR327C_mRNA; YLR327C; YLR327C.
DR GeneID; 851037; -.
DR KEGG; sce:YLR327C; -.
DR SGD; S000004319; TMA10.
DR VEuPathDB; FungiDB:YLR327C; -.
DR eggNOG; ENOG502S4WH; Eukaryota.
DR HOGENOM; CLU_186295_0_0_1; -.
DR InParanoid; Q06177; -.
DR OMA; KWTVHES; -.
DR BioCyc; YEAST:G3O-32410-MON; -.
DR PRO; PR:Q06177; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; Q06177; protein.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Mitochondrion; Phosphoprotein; Reference proteome.
FT CHAIN 1..86
FT /note="Translation machinery-associated protein 10"
FT /id="PRO_0000072270"
FT REGION 63..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 28
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT MOD_RES 79
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956,
FT ECO:0007744|PubMed:19779198"
SQ SEQUENCE 86 AA; 9834 MW; EF87B1701696D2F0 CRC64;
MTRTSKWTVH EAKSNPKYFT HNGNFGESPN HVKRGGYGKG NWGKPGDEIN DLIDSGEIKT
VFNKTRRGSN SQNNERRLSD LQQYHI