TMA16_DROME
ID TMA16_DROME Reviewed; 180 AA.
AC Q9VXY4; Q8MRV0;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Translation machinery-associated protein 16 homolog;
GN ORFNames=CG15027;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Embryo;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- SIMILARITY: Belongs to the TMA16 family. {ECO:0000305}.
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DR EMBL; AE014298; AAF48422.2; -; Genomic_DNA.
DR EMBL; AY119258; AAM51118.1; -; mRNA.
DR RefSeq; NP_572999.1; NM_132771.3.
DR AlphaFoldDB; Q9VXY4; -.
DR SMR; Q9VXY4; -.
DR IntAct; Q9VXY4; 1.
DR STRING; 7227.FBpp0073782; -.
DR PaxDb; Q9VXY4; -.
DR DNASU; 32440; -.
DR EnsemblMetazoa; FBtr0073965; FBpp0073782; FBgn0030611.
DR GeneID; 32440; -.
DR KEGG; dme:Dmel_CG15027; -.
DR UCSC; CG15027-RA; d. melanogaster.
DR FlyBase; FBgn0030611; CG15027.
DR VEuPathDB; VectorBase:FBgn0030611; -.
DR eggNOG; ENOG502RXYZ; Eukaryota.
DR GeneTree; ENSGT00390000004179; -.
DR HOGENOM; CLU_105581_0_0_1; -.
DR InParanoid; Q9VXY4; -.
DR OMA; SWFLGQI; -.
DR OrthoDB; 1541925at2759; -.
DR PhylomeDB; Q9VXY4; -.
DR BioGRID-ORCS; 32440; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 32440; -.
DR PRO; PR:Q9VXY4; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0030611; Expressed in eye disc (Drosophila) and 28 other tissues.
DR ExpressionAtlas; Q9VXY4; baseline and differential.
DR Genevisible; Q9VXY4; DM.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR Gene3D; 1.20.1440.170; -; 1.
DR InterPro; IPR021346; Tma16.
DR InterPro; IPR038356; Tma16_sf.
DR PANTHER; PTHR13349; PTHR13349; 1.
DR Pfam; PF11176; Tma16; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..180
FT /note="Translation machinery-associated protein 16 homolog"
FT /id="PRO_0000321564"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..32
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 66
FT /note="R -> T (in Ref. 3; AAM51118)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 180 AA; 21136 MW; 155B5C29DAE80228 CRC64;
MTNLRKELEK CKHPNSRKTK ALGKKARRQN NKHKVRLGHA IKSNITGEKL SWFLGQIDEG
RTEPLRPQEL EDLIELYFTR FDEELEQINL KQSIGKHRAN QHAARKDVIT MTLEKERNEF
RTGGLELMNL CDPLKLKMLR DWDGSALSVQ HLKLDLVSYN MLQRLKEQSK KKETSEQMET
