TMA16_YEAST
ID TMA16_YEAST Reviewed; 178 AA.
AC Q08687; D6W2V3;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 2.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Translation machinery-associated protein 16;
GN Name=TMA16; OrderedLocusNames=YOR252W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=9153759;
RX DOI=10.1002/(sici)1097-0061(199704)13:5<483::aid-yea105>3.0.co;2-u;
RA Poirey R., Jauniaux J.-C.;
RT "Sequencing analysis of a 36.8 kb fragment of yeast chromosome XV reveals
RT 26 open reading frames including SEC63, CDC31, SUG2, GCD1, RBL2, PNT1, PAC1
RT and VPH1.";
RL Yeast 13:483-487(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP IDENTIFICATION OF FRAMESHIFT.
RX PubMed=12748633; DOI=10.1038/nature01644;
RA Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.;
RT "Sequencing and comparison of yeast species to identify genes and
RT regulatory elements.";
RL Nature 423:241-254(2003).
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 5350 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the TMA16 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA99474.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; Z75160; CAA99474.1; ALT_FRAME; Genomic_DNA.
DR EMBL; BK006948; DAA11019.1; -; Genomic_DNA.
DR PIR; S67149; S67149.
DR RefSeq; NP_014895.2; NM_001183671.1.
DR PDB; 2KKM; NMR; -; A=38-178.
DR PDBsum; 2KKM; -.
DR AlphaFoldDB; Q08687; -.
DR BMRB; Q08687; -.
DR SMR; Q08687; -.
DR BioGRID; 34642; 76.
DR DIP; DIP-4112N; -.
DR IntAct; Q08687; 8.
DR MINT; Q08687; -.
DR STRING; 4932.YOR252W; -.
DR MaxQB; Q08687; -.
DR PaxDb; Q08687; -.
DR PRIDE; Q08687; -.
DR EnsemblFungi; YOR252W_mRNA; YOR252W; YOR252W.
DR GeneID; 854426; -.
DR KEGG; sce:YOR252W; -.
DR SGD; S000005778; TMA16.
DR VEuPathDB; FungiDB:YOR252W; -.
DR eggNOG; ENOG502RY79; Eukaryota.
DR GeneTree; ENSGT00390000004179; -.
DR HOGENOM; CLU_106785_0_0_1; -.
DR InParanoid; Q08687; -.
DR OMA; GFWMPDL; -.
DR BioCyc; YEAST:G3O-33743-MON; -.
DR EvolutionaryTrace; Q08687; -.
DR PRO; PR:Q08687; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; Q08687; protein.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR Gene3D; 1.20.1440.170; -; 1.
DR InterPro; IPR021346; Tma16.
DR InterPro; IPR038356; Tma16_sf.
DR PANTHER; PTHR13349; PTHR13349; 1.
DR Pfam; PF11176; Tma16; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Nucleus; Reference proteome.
FT CHAIN 1..178
FT /note="Translation machinery-associated protein 16"
FT /id="PRO_0000237637"
FT HELIX 55..69
FT /evidence="ECO:0007829|PDB:2KKM"
FT TURN 71..75
FT /evidence="ECO:0007829|PDB:2KKM"
FT HELIX 81..105
FT /evidence="ECO:0007829|PDB:2KKM"
FT HELIX 106..108
FT /evidence="ECO:0007829|PDB:2KKM"
FT HELIX 115..131
FT /evidence="ECO:0007829|PDB:2KKM"
FT STRAND 134..137
FT /evidence="ECO:0007829|PDB:2KKM"
FT HELIX 142..149
FT /evidence="ECO:0007829|PDB:2KKM"
FT HELIX 157..160
FT /evidence="ECO:0007829|PDB:2KKM"
FT STRAND 163..167
FT /evidence="ECO:0007829|PDB:2KKM"
FT TURN 168..170
FT /evidence="ECO:0007829|PDB:2KKM"
SQ SEQUENCE 178 AA; 20839 MW; 8C7C0FF4AD6F5ABA CRC64;
MPVTKSLSKL QKNLSKKGKN ITVHPKGRKY EKLVRATMRE DKIAAKKKLH QDKRVHELAR
VKFMQDVVNS DTFKGQPIFD HAHTREFIQS FIERDDTELD ELKKKRRSNR PPSNRQVLLQ
QRRDQELKEF KAGFLCPDLS DAKNMEFLRN WNGTFGLLNT LRLIRINDKG EQVVGGNE
