TMA7_MOUSE
ID TMA7_MOUSE Reviewed; 64 AA.
AC Q8K003;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Translation machinery-associated protein 7;
DE AltName: Full=Coiled-coil domain-containing protein 72;
GN Name=Tma7; Synonyms=Ccdc72;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and NOD; TISSUE=Embryo, and Head;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the TMA7 family. {ECO:0000305}.
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DR EMBL; AK003762; BAC25052.1; -; mRNA.
DR EMBL; AK160705; BAE35964.1; -; mRNA.
DR EMBL; AK169860; BAE41416.1; -; mRNA.
DR EMBL; BC106104; AAI06105.1; -; mRNA.
DR CCDS; CCDS52930.1; -.
DR RefSeq; NP_899073.1; NM_183250.2.
DR AlphaFoldDB; Q8K003; -.
DR BioGRID; 211265; 3.
DR STRING; 10090.ENSMUSP00000133026; -.
DR iPTMnet; Q8K003; -.
DR PhosphoSitePlus; Q8K003; -.
DR EPD; Q8K003; -.
DR MaxQB; Q8K003; -.
DR PaxDb; Q8K003; -.
DR PRIDE; Q8K003; -.
DR ProteomicsDB; 259120; -.
DR TopDownProteomics; Q8K003; -.
DR Antibodypedia; 45855; 24 antibodies from 13 providers.
DR Ensembl; ENSMUST00000167504; ENSMUSP00000133026; ENSMUSG00000091537.
DR GeneID; 66167; -.
DR KEGG; mmu:66167; -.
DR UCSC; uc009rrw.1; mouse.
DR CTD; 51372; -.
DR MGI; MGI:1913417; Tma7.
DR VEuPathDB; HostDB:ENSMUSG00000091537; -.
DR eggNOG; KOG4766; Eukaryota.
DR GeneTree; ENSGT00390000003710; -.
DR HOGENOM; CLU_184661_1_1_1; -.
DR InParanoid; Q8K003; -.
DR OMA; KKGPMNT; -.
DR TreeFam; TF300250; -.
DR BioGRID-ORCS; 66167; 4 hits in 71 CRISPR screens.
DR ChiTaRS; Tma7; mouse.
DR PRO; PR:Q8K003; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q8K003; protein.
DR Bgee; ENSMUSG00000091537; Expressed in layer of retina and 65 other tissues.
DR ExpressionAtlas; Q8K003; baseline and differential.
DR Genevisible; Q8K003; MM.
DR InterPro; IPR015157; TMA7.
DR PANTHER; PTHR28632; PTHR28632; 1.
DR Pfam; PF09072; TMA7; 1.
PE 3: Inferred from homology;
KW ADP-ribosylation; Coiled coil; Reference proteome.
FT CHAIN 1..64
FT /note="Translation machinery-associated protein 7"
FT /id="PRO_0000235682"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 21..50
FT /evidence="ECO:0000255"
FT COMPBIAS 16..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 61
FT /note="ADP-ribosylserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2S6"
SQ SEQUENCE 64 AA; 7066 MW; E79BA054EC176B74 CRC64;
MSGREGGKKK PLKQPKKQAK EMDEEDKAFK QKQKEEQKKL EELKAKAAGK GPLATGGIKK
SGKK