ID   AC4_TPCTV               Reviewed;          85 AA.
AC   Q88891;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Protein C4;
DE   AltName: Full=Protein L4;
GN   ORFNames=C4, L4;
OS   Tomato pseudo-curly top virus (TPCTV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Topocuvirus.
OX   NCBI_TaxID=49267;
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH   NCBI_TaxID=4112; Solanum nigrum (Black nightshade).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8638404; DOI=10.1006/viro.1996.0264;
RA   Briddon R.W., Bedford I.D., Tsai J.H., Markham P.G.;
RT   "Analysis of the nucleotide sequence of the treehopper-transmitted
RT   geminivirus, tomato pseudo-curly top virus, suggests a recombinant
RT   origin.";
RL   Virology 219:387-394(1996).
CC   -!- FUNCTION: Pathogenicity determinant (By similarity). May act as a
CC       suppressor of RNA-mediated gene silencing, also known as post-
CC       transcriptional gene silencing (PTGS), a mechanism of plant viral
CC       defense that limits the accumulation of viral RNAs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000250}. Note=Localizes to the cell periphery. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae protein AC4/C4 family.
CC       {ECO:0000305}.
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DR   EMBL; X84735; CAA59226.1; -; Genomic_DNA.
DR   RefSeq; NP_620736.1; NC_003825.1.
DR   SMR; Q88891; -.
DR   GeneID; 944408; -.
DR   KEGG; vg:944408; -.
DR   Proteomes; UP000007068; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR002488; Gemini_C4.
DR   Pfam; PF01492; Gemini_C4; 1.
PE   3: Inferred from homology;
KW   Host cell membrane; Host membrane; Lipoprotein; Membrane; Myristate;
KW   Reference proteome; Suppressor of RNA silencing.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..85
FT                   /note="Protein C4"
FT                   /id="PRO_0000323705"
FT   REGION          42..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           2
FT                   /note="N-myristoyl glycine; by host"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   85 AA;  9456 MW;  22F6C11CC97677F7 CRC64;
     MGNLISMCLY NSKGNSTAKI NDSSTWYPQP GQHISIRTYR ELNPAPTSTP TSTRTETLSN
     GENSRLTLDL LEEASRQLTT NVQRP