TMA7_YEAST
ID TMA7_YEAST Reviewed; 64 AA.
AC Q3E764; D6VYQ9;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Translation machinery-associated protein 7;
GN Name=TMA7; OrderedLocusNames=YLR262C-A;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP FUNCTION, IDENTIFICATION BY MASS SPECTROMETRY, AND SUBUNIT.
RX PubMed=16702403; DOI=10.1101/gad.1422006;
RA Fleischer T.C., Weaver C.M., McAfee K.J., Jennings J.L., Link A.J.;
RT "Systematic identification and functional screens of uncharacterized
RT proteins associated with eukaryotic ribosomal complexes.";
RL Genes Dev. 20:1294-1307(2006).
CC -!- FUNCTION: Involved in protein synthesis. {ECO:0000269|PubMed:16702403}.
CC -!- SUBUNIT: Interacts with the 40S ribosomal subunit.
CC {ECO:0000269|PubMed:16702403}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus
CC {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 3100 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the TMA7 family. {ECO:0000305}.
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DR EMBL; U17244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BK006945; DAA09575.1; -; Genomic_DNA.
DR RefSeq; NP_013364.1; NM_001184339.1.
DR AlphaFoldDB; Q3E764; -.
DR BioGRID; 31530; 47.
DR IntAct; Q3E764; 3.
DR MINT; Q3E764; -.
DR STRING; 4932.YLR262C-A; -.
DR iPTMnet; Q3E764; -.
DR MaxQB; Q3E764; -.
DR PaxDb; Q3E764; -.
DR PRIDE; Q3E764; -.
DR TopDownProteomics; Q3E764; -.
DR EnsemblFungi; YLR262C-A_mRNA; YLR262C-A; YLR262C-A.
DR GeneID; 850967; -.
DR KEGG; sce:YLR262C-A; -.
DR SGD; S000007246; TMA7.
DR VEuPathDB; FungiDB:YLR262C-A; -.
DR eggNOG; KOG4766; Eukaryota.
DR HOGENOM; CLU_184661_2_0_1; -.
DR InParanoid; Q3E764; -.
DR OMA; KKGPMNT; -.
DR BioCyc; YEAST:G3O-32560-MON; -.
DR PRO; PR:Q3E764; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; Q3E764; protein.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR InterPro; IPR015157; TMA7.
DR PANTHER; PTHR28632; PTHR28632; 1.
DR Pfam; PF09072; TMA7; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Nucleus; Protein biosynthesis; Reference proteome.
FT CHAIN 1..64
FT /note="Translation machinery-associated protein 7"
FT /id="PRO_0000247142"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 45..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 64 AA; 6941 MW; D46DEAA03FB98ADC CRC64;
MSSRQGGKMK PLKQKKKQQQ DLDPEDIAFK EKQKADAAAK KALMANMKSG KPLVGGGIKK
SGKK
