BT3L4_MOUSE
ID BT3L4_MOUSE Reviewed; 158 AA.
AC Q9CQH7;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Transcription factor BTF3 homolog 4;
DE AltName: Full=Basic transcription factor 3-like 4;
GN Name=Btf3l4;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Skin;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6NCr; TISSUE=Hematopoietic stem cell, and Oocyte;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
RC Spleen, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the NAC-beta family. {ECO:0000305}.
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DR EMBL; AK004239; BAB23233.1; -; mRNA.
DR EMBL; AK011367; BAB27573.1; -; mRNA.
DR EMBL; AK013120; BAB28660.1; -; mRNA.
DR EMBL; AK076283; BAC36287.1; -; mRNA.
DR EMBL; BC058282; AAH58282.1; -; mRNA.
DR EMBL; BC099407; AAH99407.1; -; mRNA.
DR CCDS; CCDS18456.1; -.
DR RefSeq; NP_081729.1; NM_027453.2.
DR RefSeq; XP_006503453.1; XM_006503390.1.
DR RefSeq; XP_006503454.1; XM_006503391.1.
DR RefSeq; XP_011238913.1; XM_011240611.2.
DR RefSeq; XP_011238914.1; XM_011240612.1.
DR AlphaFoldDB; Q9CQH7; -.
DR SMR; Q9CQH7; -.
DR BioGRID; 214117; 3.
DR STRING; 10090.ENSMUSP00000099803; -.
DR iPTMnet; Q9CQH7; -.
DR PhosphoSitePlus; Q9CQH7; -.
DR REPRODUCTION-2DPAGE; Q9CQH7; -.
DR EPD; Q9CQH7; -.
DR jPOST; Q9CQH7; -.
DR MaxQB; Q9CQH7; -.
DR PaxDb; Q9CQH7; -.
DR PRIDE; Q9CQH7; -.
DR ProteomicsDB; 273776; -.
DR DNASU; 70533; -.
DR Ensembl; ENSMUST00000102739; ENSMUSP00000099800; ENSMUSG00000028568.
DR Ensembl; ENSMUST00000102740; ENSMUSP00000099801; ENSMUSG00000028568.
DR Ensembl; ENSMUST00000102741; ENSMUSP00000099802; ENSMUSG00000028568.
DR Ensembl; ENSMUST00000102742; ENSMUSP00000099803; ENSMUSG00000028568.
DR Ensembl; ENSMUST00000220449; ENSMUSP00000152074; ENSMUSG00000114133.
DR GeneID; 70533; -.
DR KEGG; mmu:70533; -.
DR UCSC; uc008ubo.1; mouse.
DR CTD; 91408; -.
DR MGI; MGI:1915312; Btf3l4.
DR VEuPathDB; HostDB:ENSMUSG00000028568; -.
DR VEuPathDB; HostDB:ENSMUSG00000114133; -.
DR eggNOG; KOG2240; Eukaryota.
DR GeneTree; ENSGT00940000154296; -.
DR HOGENOM; CLU_098726_3_0_1; -.
DR InParanoid; Q9CQH7; -.
DR OMA; QLGPENI; -.
DR OrthoDB; 1435264at2759; -.
DR PhylomeDB; Q9CQH7; -.
DR TreeFam; TF317546; -.
DR BioGRID-ORCS; 70533; 2 hits in 73 CRISPR screens.
DR ChiTaRS; Btf3l4; mouse.
DR PRO; PR:Q9CQH7; -.
DR Proteomes; UP000000589; Chromosome 13.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q9CQH7; protein.
DR Bgee; ENSMUSG00000028568; Expressed in ventricular zone and 229 other tissues.
DR ExpressionAtlas; Q9CQH7; baseline and differential.
DR Genevisible; Q9CQH7; MM.
DR Gene3D; 2.20.70.30; -; 1.
DR InterPro; IPR039370; BTF3.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR PANTHER; PTHR10351; PTHR10351; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 1: Evidence at protein level;
KW Methylation; Phosphoprotein; Reference proteome.
FT CHAIN 1..158
FT /note="Transcription factor BTF3 homolog 4"
FT /id="PRO_0000213558"
FT DOMAIN 33..98
FT /note="NAC-A/B"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00507"
FT REGION 122..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 5
FT /note="N6-methyllysine"
FT /evidence="ECO:0000250|UniProtKB:P20290"
FT MOD_RES 111
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:P20290"
SQ SEQUENCE 158 AA; 17271 MW; 8C4AD058FB92D722 CRC64;
MNQEKLAKLQ AQVRIGGKGT ARRKKKVVHR TATADDKKLQ SSLKKLAVNN IAGIEEVNMI
KDDGTVIHFN NPKVQASLSA NTFAITGHAE AKPITEMLPG ILSQLGADSL TSLRKLAEQF
PRQVLDSKAP KPEDIDEEDD DVPDLVENFD EASKNEAN
