ID   AC4_TYCS1               Reviewed;          96 AA.
AC   P38612;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   29-SEP-2021, entry version 54.
DE   RecName: Full=Protein C4;
DE   AltName: Full=10.9 kDa protein;
DE   AltName: Full=Protein L4;
GN   ORFNames=C4, L4;
OS   Tomato yellow leaf curl Sardinia virus (isolate Spain-1) (TYLCSV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=37139;
OH   NCBI_TaxID=185024; Cynanchum acutum.
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH   NCBI_TaxID=4112; Solanum nigrum (Black nightshade).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8198442; DOI=10.1007/bf01309774;
RA   Noris E., Hidalgo E., Accotto G.P., Moriones E.;
RT   "High similarity among the tomato yellow leaf curl virus isolates from the
RT   west Mediterranean basin: the nucleotide sequence of an infectious clone
RT   from Spain.";
RL   Arch. Virol. 135:165-170(1994).
CC   -!- FUNCTION: Pathogenicity determinant (By similarity). May act as a
CC       suppressor of RNA-mediated gene silencing, also known as post-
CC       transcriptional gene silencing (PTGS), a mechanism of plant viral
CC       defense that limits the accumulation of viral RNAs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000250}. Note=Localizes to the cell periphery. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae protein AC4/C4 family.
CC       {ECO:0000305}.
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DR   EMBL; Z25751; CAA81029.1; -; Genomic_DNA.
DR   Proteomes; UP000008265; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR002488; Gemini_C4.
DR   Pfam; PF01492; Gemini_C4; 1.
PE   3: Inferred from homology;
KW   Host cell membrane; Host membrane; Lipoprotein; Membrane; Myristate;
KW   Suppressor of RNA silencing.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..96
FT                   /note="Protein C4"
FT                   /id="PRO_0000222298"
FT   REGION          66..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           2
FT                   /note="N-myristoyl glycine; by host"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   96 AA;  10850 MW;  A1C3693B03E327FC CRC64;
     MGNLISTCSF SSRVNSTAKI TDSSIWYPQP DQHISIRTFR ELNQAPTSSP TSTRTEMFLN
     GVLSRSTDDL QGEDSRQPMT LTPRQLTQEV SRRLLM