ID   TMCO4_CAEEL             Reviewed;         617 AA.
AC   Q20035;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 2.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Uncharacterized membrane protein F35D11.3;
GN   ORFNames=F35D11.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMCO4 family. {ECO:0000305}.
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DR   EMBL; FO081293; CCD70531.1; -; Genomic_DNA.
DR   PIR; T16263; T16263.
DR   RefSeq; NP_494812.2; NM_062411.5.
DR   AlphaFoldDB; Q20035; -.
DR   STRING; 6239.F35D11.3.1; -.
DR   ESTHER; caeel-tmco4; Duf_726.
DR   EPD; Q20035; -.
DR   PaxDb; Q20035; -.
DR   PRIDE; Q20035; -.
DR   EnsemblMetazoa; F35D11.3.1; F35D11.3.1; WBGene00018044.
DR   GeneID; 173798; -.
DR   KEGG; cel:CELE_F35D11.3; -.
DR   UCSC; F35D11.3.1; c. elegans.
DR   CTD; 173798; -.
DR   WormBase; F35D11.3; CE31803; WBGene00018044; -.
DR   eggNOG; KOG2385; Eukaryota.
DR   GeneTree; ENSGT00390000001400; -.
DR   HOGENOM; CLU_016865_0_2_1; -.
DR   InParanoid; Q20035; -.
DR   OMA; EHISWSW; -.
DR   OrthoDB; 1281288at2759; -.
DR   PhylomeDB; Q20035; -.
DR   PRO; PR:Q20035; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00018044; Expressed in material anatomical entity and 4 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR007941; DUF726.
DR   PANTHER; PTHR17920; PTHR17920; 1.
DR   Pfam; PF05277; DUF726; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..617
FT                   /note="Uncharacterized membrane protein F35D11.3"
FT                   /id="PRO_0000305152"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  67343 MW;  F353344210A62DAC CRC64;
     MSKCATPTPS TSSNSSDEAK RSPQPMSRGF PQRNMSTTSS NGSNSPRHRS LETPIVLQPA
     TRFALANLTT TVLRLDFWDD NDPNSIFFCK STFNIVTQCL DLPEKVIKTV KTHLEGEEDL
     TDIAPMIMSV REDPVYKTEG STPFLASLLV AFVNQGNYDS RYRVFLRHLT TLLGVVWTEF
     EDVEDSLAST LLEEQFVESE HSRTVREKTA RNKKIKRYLM IGAAGGVGGV LIGLTGGLAA
     PLVAASAGML IGGGAVAGLA TTAGAAVLGT TMGVAGAGFT GYKMKKRVGA IEEFSVETLS
     EGVSLSCSLV VSGWIESDTS PDQAFVHQWR HLRHTKEQYT LRYESNYLME LGNAIEYLMS
     FAVSVAIQQT LLETALAGLV SAVAWPVALM SVSSVLDNPW NVCVSRAAEV GEQLAEVLLS
     RSHGKRPITL IGFSLGARVI FHCLLTMSKR SESVGIIEDV ILLGAPVTAS PKEWSKVCTV
     VSGRVINGYC ETDWLLRFLY RTMSAQFRIA GTGPIDNRNS KKIYNYNLSH IVKGHMDYSK
     RLTEVLNAVG VKVGPHSEDS VVDLTQLEGP HEATGQAEEA INYQSTGEEE EHPIVHPINL
     ENIHEVKVLD SPHKNEF