BTB7_MYCTU
ID BTB7_MYCTU Reviewed; 71 AA.
AC P9WPQ1; L0TBW3; O05845; P0A510;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Biotinylated protein TB7.3;
GN OrderedLocusNames=Rv3221c; ORFNames=MTCY07D11.05;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP PROTEIN SEQUENCE OF 2-16, AND BIOTINYLATION.
RX PubMed=10603390; DOI=10.1128/iai.68.1.214-220.2000;
RA Skjot R.L., Oettinger T., Rosenkrands I., Ravn P., Brock I., Jacobsen S.,
RA Andersen P.;
RT "Comparative evaluation of low-molecular-mass proteins from Mycobacterium
RT tuberculosis identifies members of the ESAT-6 family as immunodominant T-
RT cell antigens.";
RL Infect. Immun. 68:214-220(2000).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL123456; CCP46037.1; -; Genomic_DNA.
DR PIR; F70596; F70596.
DR RefSeq; NP_217737.1; NC_000962.3.
DR RefSeq; WP_003416887.1; NZ_NVQJ01000003.1.
DR AlphaFoldDB; P9WPQ1; -.
DR SMR; P9WPQ1; -.
DR STRING; 83332.Rv3221c; -.
DR PaxDb; P9WPQ1; -.
DR DNASU; 888096; -.
DR GeneID; 45427214; -.
DR GeneID; 888096; -.
DR KEGG; mtu:Rv3221c; -.
DR TubercuList; Rv3221c; -.
DR eggNOG; COG1038; Bacteria.
DR OMA; MAGNLWK; -.
DR PhylomeDB; P9WPQ1; -.
DR Proteomes; UP000001584; Chromosome.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR011053; Single_hybrid_motif.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR SUPFAM; SSF51230; SSF51230; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
PE 1: Evidence at protein level;
KW Biotin; Direct protein sequencing; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:10603390"
FT CHAIN 2..71
FT /note="Biotinylated protein TB7.3"
FT /id="PRO_0000146838"
FT DOMAIN 2..71
FT /note="Biotinyl-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
FT MOD_RES 37
FT /note="N6-biotinyllysine"
FT /evidence="ECO:0000250, ECO:0000255|PROSITE-
FT ProRule:PRU01066"
SQ SEQUENCE 71 AA; 7306 MW; 91E74BE43A76EFBB CRC64;
MAEDVRAEIV ASVLEVVVNE GDQIDKGDVV VLLESMKMEI PVLAEAAGTV SKVAVSVGDV
IQAGDLIAVI S