BTBBB_DANRE
ID BTBBB_DANRE Reviewed; 1012 AA.
AC P0C7A6; Q1LVL9;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Ankyrin repeat and BTB/POZ domain-containing protein BTBD11-B;
DE AltName: Full=BTB/POZ domain-containing protein 11-B;
GN Name=btbd11b; Synonyms=btbd11;
GN ORFNames=si:ch211-170d11.3, si:dkey-264l19.1;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAK04227.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; BX571976; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BX649610; CAK04227.2; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; P0C7A6; -.
DR SMR; P0C7A6; -.
DR STRING; 7955.ENSDARP00000086175; -.
DR PaxDb; P0C7A6; -.
DR ZFIN; ZDB-GENE-050419-99; btbd11b.
DR eggNOG; ENOG502QSQY; Eukaryota.
DR InParanoid; P0C7A6; -.
DR PhylomeDB; P0C7A6; -.
DR PRO; PR:P0C7A6; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0060395; P:SMAD protein signal transduction; IBA:GO_Central.
DR Gene3D; 1.10.20.10; -; 1.
DR Gene3D; 1.25.40.20; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF47113; SSF47113; 2.
DR SUPFAM; SSF48403; SSF48403; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW ANK repeat; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1012
FT /note="Ankyrin repeat and BTB/POZ domain-containing protein
FT BTBD11-B"
FT /id="PRO_0000328829"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 511..540
FT /note="ANK 1"
FT REPEAT 557..586
FT /note="ANK 2"
FT REPEAT 595..624
FT /note="ANK 3"
FT DOMAIN 831..897
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ SEQUENCE 1012 AA; 113196 MW; 2A87CC9924EBD851 CRC64;
MAKRGKSVVR TLEDLTLDSG YGGAADSFRS SSLSLCCSEA HISYAHGGHC WNLTDSMRSR
HNSLDTVNTV LAEDGETLEC SGHCAKLPEL EDVPWSLGEV ENALNKEEEL RFGTVSADLL
ARLSALVCRA LVRIAREAQR LSLRYGKCTK YEVQSAIKMI LSWTISVNCI AASLSALSMY
NMSTEDKFSR GKSERCGLVF SVGKFFRWMV DSRVAVRVHE HAAIYLTGCM ESLFREVFTR
VLNSSVVEKD NGIPKFTLES FEQALSNDSE LYGLLLPYQH LTCGKNANGI LSLPDSLSLH
RNQQCSSKAG DAYSQSEQRT IEQSLLATRV GSIAELSDLV SRAMHYLQPL SIKNHSNGTP
LPQKSSLVHW EPEALYTLCY FMHCPQMEWE NPNVEPSKVT LQNERPFLVL PPLMEWIRVA
LAHAEHRRSF SVDSDDVRQA ARLLLPGVDC EPRQLKTDDC FCVSRKLDAA STEAKFLQDL
GFRMLNCGRT DLVNQAINLL GPGGINSMSE QGMTPLMYAC VRGDEAMVQM LLDAGADINS
EVPNTVQKFP SVFPETRQAT PLTFAVLHQH IPVVQLLLDA GANVEGSLQD GMENYTETPL
QLASAAGNFE LVSLLLERGA DPMIGTMYRN GISTAPHGDM NSYSLAAAHG HRNVFCKLLS
QSEKGKADVL SLQEILAEGS DLEERNSLKM EATRTGKAKL KALREAMYHS SEHGYVDITL
DIRSLGVPWT LHTWLESLRT CFLQHRRPLI QGLLKEFSSI EEEEYTEELI THGLPLMFQI
LRASKNEVIS QQLAVIFTQC YGPYPIPKLT EIKRKQTSRL DPHFLNNKEM SDVTFLVEGK
PFYAHKVLLF TASNRFKLLL ANRPAAENTC IEISHVKYNV FQLVMQYLYC GGTDALHIRN
TEVMDLLSAS KFFQLEALQR HCEIICAKNI NTETCVEIYN HAKFLEAPEL SAYIEGYFLK
NMAVLIELEP FKQLLYNTPV ENCCPDVLHD LEKTLATRIR SIHLSSSKGS IV
