TMM19_PONAB
ID TMM19_PONAB Reviewed; 336 AA.
AC Q5RF73;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=Transmembrane protein 19;
GN Name=TMEM19;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM19 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR857288; CAH89584.1; -; mRNA.
DR RefSeq; NP_001124699.1; NM_001131227.2.
DR RefSeq; XP_009246307.1; XM_009248032.1.
DR RefSeq; XP_009246308.1; XM_009248033.1.
DR RefSeq; XP_009246309.1; XM_009248034.1.
DR RefSeq; XP_009246310.1; XM_009248035.1.
DR AlphaFoldDB; Q5RF73; -.
DR STRING; 9601.ENSPPYP00000005440; -.
DR Ensembl; ENSPPYT00000005653; ENSPPYP00000005440; ENSPPYG00000004775.
DR GeneID; 100171546; -.
DR KEGG; pon:100171546; -.
DR CTD; 55266; -.
DR eggNOG; KOG4491; Eukaryota.
DR GeneTree; ENSGT00390000017998; -.
DR InParanoid; Q5RF73; -.
DR OrthoDB; 1476886at2759; -.
DR Proteomes; UP000001595; Chromosome 12.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR002794; DUF92_TMEM19.
DR PANTHER; PTHR13353; PTHR13353; 1.
DR Pfam; PF01940; DUF92; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..336
FT /note="Transmembrane protein 19"
FT /id="PRO_0000284796"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 336 AA; 36439 MW; FFB4BB1C43BF044F CRC64;
MTDLNDNICK RYIKMITNIV ILSLIICISL AFWIMSMTAS TYYGNLRPIS PWRWLFSVVV
PVLIISNGLK KKSLDHSGAL GGLVVGFILT IANFSFFTSL LMFFLSSSKL TKWKGEMKKR
LDSEYKEGGQ RNWIQVFCNG AVPTELALLY MIENGPGEIP VDFSKQYSAS WMCLSLLAAL
ACSAGDTWAS EVGPVLSKSP PRLITTWEKV PVGTNGGVTV VGLVSSLLGG TFVGIAYFLT
QLIFVNDLDI SAPQWPIIAF GGLAGLLGSI VDSYLGATMQ YTGLDESTGM VVNSPTNEAK
HIAGKPILDN NAVNLFSSVL IAVLLPTAAW GFWPRG