TMM19_RAT
ID TMM19_RAT Reviewed; 351 AA.
AC Q6P726;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 17-APR-2007, sequence version 2.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Transmembrane protein 19;
GN Name=Tmem19;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Prostate;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM19 family. {ECO:0000305}.
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DR EMBL; BC061871; AAH61871.1; -; mRNA.
DR RefSeq; NP_954529.1; NM_199098.1.
DR AlphaFoldDB; Q6P726; -.
DR STRING; 10116.ENSRNOP00000005310; -.
DR iPTMnet; Q6P726; -.
DR PhosphoSitePlus; Q6P726; -.
DR PaxDb; Q6P726; -.
DR GeneID; 299800; -.
DR KEGG; rno:299800; -.
DR CTD; 55266; -.
DR RGD; 735209; Tmem19.
DR eggNOG; KOG4491; Eukaryota.
DR HOGENOM; CLU_036918_3_1_1; -.
DR InParanoid; Q6P726; -.
DR OrthoDB; 1476886at2759; -.
DR PhylomeDB; Q6P726; -.
DR TreeFam; TF300063; -.
DR PRO; PR:Q6P726; -.
DR Proteomes; UP000002494; Unplaced.
DR Genevisible; Q6P726; RN.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR002794; DUF92_TMEM19.
DR PANTHER; PTHR13353; PTHR13353; 1.
DR Pfam; PF01940; DUF92; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..351
FT /note="Transmembrane protein 19"
FT /id="PRO_0000284797"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 351 AA; 37750 MW; 36C2023FC46220D1 CRC64;
MLSIPSPQVL LALFSMTDLD DSTCKKYIKM ITNIVILSLI ICISLAFWIM SMTASTYYGS
LRPVSPWRWL FSVVVSVVIS CNGFKKKSLD HSGALGGLVV GFILTIANFS FFTSLLMFFL
TSSKLTKWRG EMKKRLDSEY KEGGQRNWVQ VFCNGGVPTE LALLYMIENG PGEMPIDFAK
QHTASWMCLS LLAALASSAG DTWASEVAPV LSKSSPRLIT TWEKVPVGTN GGVTAVGLVS
SLLGGTFVGL AYFLTQLVFV NDLDISAPQW PLIAFGGLAG LLGSIVDSFL GATMQFSGLD
ESTGLVVSSP TQETKHISGK PILDNNAVNL FSSVLVALLL PTAASGFWPT V