ID   TMM47_XENTR             Reviewed;         179 AA.
AC   Q6PBE5;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Transmembrane protein 47;
DE   AltName: Full=Transmembrane 4 superfamily member 10;
GN   Name=tmem47; Synonyms=tm4sf10;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulates cell junction organization in epithelial cells. May
CC       play a role in the transition from adherens junction to tight junction
CC       assembly. {ECO:0000250|UniProtKB:Q9JJG6, ECO:0000250|UniProtKB:Q9XSV3}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Cell junction, adherens junction
CC       {ECO:0000250|UniProtKB:Q9XSV3}.
CC   -!- SIMILARITY: Belongs to the TMEM47 family. {ECO:0000305}.
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DR   EMBL; BC059749; AAH59749.1; -; mRNA.
DR   RefSeq; NP_988899.1; NM_203568.1.
DR   AlphaFoldDB; Q6PBE5; -.
DR   SMR; Q6PBE5; -.
DR   STRING; 8364.ENSXETP00000056751; -.
DR   PaxDb; Q6PBE5; -.
DR   DNASU; 394494; -.
DR   Ensembl; ENSXETT00000056751; ENSXETP00000056751; ENSXETG00000027069.
DR   GeneID; 394494; -.
DR   KEGG; xtr:394494; -.
DR   CTD; 83604; -.
DR   Xenbase; XB-GENE-951338; tmem47.
DR   eggNOG; KOG4671; Eukaryota.
DR   HOGENOM; CLU_120054_1_0_1; -.
DR   InParanoid; Q6PBE5; -.
DR   OMA; AENLWIC; -.
DR   OrthoDB; 1307601at2759; -.
DR   PhylomeDB; Q6PBE5; -.
DR   TreeFam; TF312855; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027069; Expressed in heart and 8 other tissues.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005911; C:cell-cell junction; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0098609; P:cell-cell adhesion; IBA:GO_Central.
DR   InterPro; IPR019372; LHFPL.
DR   InterPro; IPR015664; P53_induced.
DR   PANTHER; PTHR14399; PTHR14399; 1.
DR   Pfam; PF10242; L_HMGIC_fpl; 1.
PE   2: Evidence at transcript level;
KW   Cell junction; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..179
FT                   /note="Transmembrane protein 47"
FT                   /id="PRO_0000072576"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   179 AA;  19783 MW;  D1FE12BA7C21EA07 CRC64;
     MASSASGMEE VRSSVLTPLK LVGLVCIFLA LCLDIGAVLS PAWVTADNQY YLSLWESCKK
     AENLWICDST LESDWQIATL ALLLGGAAII LIAFLVGLIS ICVGSRRRFY RPVAVMLFAA
     VVLQVCGLVL YPIKFIETVT LKIYHEFNWG YGLAWGATIF SFGGAILYCL NPKNYEDYY