ID   TMM53_BOVIN             Reviewed;         294 AA.
AC   Q2TBP5;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Transmembrane protein 53;
GN   Name=TMEM53;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM53 family. {ECO:0000305}.
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DR   EMBL; BC109854; AAI09855.1; -; mRNA.
DR   RefSeq; NP_001033661.1; NM_001038572.1.
DR   AlphaFoldDB; Q2TBP5; -.
DR   STRING; 9913.ENSBTAP00000016415; -.
DR   ESTHER; bovin-tmm53; Duf_829.
DR   PaxDb; Q2TBP5; -.
DR   GeneID; 540738; -.
DR   KEGG; bta:540738; -.
DR   CTD; 79639; -.
DR   eggNOG; KOG2521; Eukaryota.
DR   HOGENOM; CLU_036503_1_2_1; -.
DR   InParanoid; Q2TBP5; -.
DR   OrthoDB; 916101at2759; -.
DR   TreeFam; TF313176; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR008547; DUF829_TMEM53.
DR   PANTHER; PTHR12265; PTHR12265; 1.
DR   Pfam; PF05705; DUF829; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..294
FT                   /note="Transmembrane protein 53"
FT                   /id="PRO_0000284117"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   294 AA;  33161 MW;  859C0F83CEB98CF8 CRC64;
     MASAQLDYTI EIPDQPCRSQ ENSPDQGGKE AGTRLPLVIL LGWGGCSDKN LAKYSAIYHK
     RGCIVIRYTA PWHMVFFSET LGIPSLRVLA QKLLELLFDY EVEKEPLLFH VFSNAGVMLY
     RYVLELLQTH QRFCHLRVVG TIFDSGPGDS NLLGALRALA VVLEHRPAAL RLLLLVAFTL
     VAFLFHVLLA PLTALFHTHF YDRLLDAASR WPELYLYSRA DEVVLARDVE RMVEARLAHQ
     VLVRSVDFVS SAHVSHLRDY PTYYTTLCIN FMHSCVHCSG PCPPHLTSAP EINA