ID   TMM54_BOVIN             Reviewed;         222 AA.
AC   Q3ZCD2;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Transmembrane protein 54;
GN   Name=TMEM54;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM54 family. {ECO:0000305}.
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DR   EMBL; BC102511; AAI02512.1; -; mRNA.
DR   RefSeq; NP_001029536.1; NM_001034364.2.
DR   AlphaFoldDB; Q3ZCD2; -.
DR   STRING; 9913.ENSBTAP00000037867; -.
DR   PaxDb; Q3ZCD2; -.
DR   Ensembl; ENSBTAT00000038048; ENSBTAP00000037867; ENSBTAG00000008331.
DR   GeneID; 509773; -.
DR   KEGG; bta:509773; -.
DR   CTD; 113452; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008331; -.
DR   VGNC; VGNC:36097; TMEM54.
DR   eggNOG; ENOG502S0UN; Eukaryota.
DR   GeneTree; ENSGT00390000004700; -.
DR   HOGENOM; CLU_089663_1_0_1; -.
DR   InParanoid; Q3ZCD2; -.
DR   OMA; FAVRCSQ; -.
DR   OrthoDB; 1133009at2759; -.
DR   TreeFam; TF332771; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000008331; Expressed in esophagus and 81 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR020977; Beta-casein-like.
DR   PANTHER; PTHR31258; PTHR31258; 1.
DR   Pfam; PF12304; BCLP; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..222
FT                   /note="Transmembrane protein 54"
FT                   /id="PRO_0000226988"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          198..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   222 AA;  23646 MW;  E9A619D245949452 CRC64;
     MCLRLGGLSV GDFRKVLMKT GLVLVVLGHV SFIAAALLHG TVLRYVAAPN DAVALQYCVV
     DILSVTSAIV VITSGISVIV LSRYLPSIPL RWTVFSSSVA CALLSLTCAL GLLASIAMTF
     ATQGRALLAA CTFGGPERLA LAPDCPFDPT RIYSSSLCLW GISLLFCVAE SVFAVRSAQL
     AYQVLELRPW LGKSSHRMMQ ESPEPVEDPD LPSRTSSGPM TL