ID   TMM69_XENTR             Reviewed;         253 AA.
AC   Q0V9J0;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Transmembrane protein 69;
GN   Name=tmem69;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Lung;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC121528; AAI21529.1; -; mRNA.
DR   RefSeq; NP_001016103.1; NM_001016103.3.
DR   RefSeq; XP_012816507.1; XM_012961053.2.
DR   RefSeq; XP_012816509.1; XM_012961055.2.
DR   RefSeq; XP_012816510.1; XM_012961056.2.
DR   AlphaFoldDB; Q0V9J0; -.
DR   STRING; 8364.ENSXETP00000054516; -.
DR   PaxDb; Q0V9J0; -.
DR   DNASU; 548857; -.
DR   Ensembl; ENSXETT00000054516; ENSXETP00000054516; ENSXETG00000025626.
DR   GeneID; 548857; -.
DR   KEGG; xtr:548857; -.
DR   CTD; 51249; -.
DR   Xenbase; XB-GENE-1014364; tmem69.
DR   eggNOG; ENOG502RYSE; Eukaryota.
DR   HOGENOM; CLU_095371_0_0_1; -.
DR   InParanoid; Q0V9J0; -.
DR   OMA; CADKEIA; -.
DR   OrthoDB; 1516042at2759; -.
DR   PhylomeDB; Q0V9J0; -.
DR   TreeFam; TF336126; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000025626; Expressed in skeletal muscle tissue and 13 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR021836; DUF3429.
DR   PANTHER; PTHR15887; PTHR15887; 1.
DR   Pfam; PF11911; DUF3429; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..253
FT                   /note="Transmembrane protein 69"
FT                   /id="PRO_0000282852"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   253 AA;  28090 MW;  8DCE99AA77D60B6C CRC64;
     MSYLRRCLPL AQQITLLNQP AAPVYSICRQ RLFSTSSRSF TKTYLFTLDR PILQSTTSTL
     SGQHKIHTSA HHFKKRKIQE ETQKHELDLL RYDIKALKDA PKPALYLGLA GLIPFVSAPL
     LMNVTGCYYP EVAFAQVAYG ASILSFLGGV RWGFAIPENS PAKPDWMNLT NSTVPALLAW
     LALLFRDNIT EAAVLVIMGL GIALHYDLAL LPTYPSWFKA LRAILTVVAV FSLVGSLINS
     SVYPHKSLVS QEP