TMM71_MOUSE
ID TMM71_MOUSE Reviewed; 287 AA.
AC Q149F5; Q8C2F7;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Transmembrane protein 71;
GN Name=Tmem71;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=NOD; TISSUE=Dendritic cell, and Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TMEM71 family. {ECO:0000305}.
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DR EMBL; AK088711; BAC40519.1; -; mRNA.
DR EMBL; AK170268; BAE41673.1; -; mRNA.
DR EMBL; BC117823; AAI17824.1; -; mRNA.
DR EMBL; BC117824; AAI17825.1; -; mRNA.
DR CCDS; CCDS37090.1; -.
DR RefSeq; NP_766102.1; NM_172514.3.
DR AlphaFoldDB; Q149F5; -.
DR SMR; Q149F5; -.
DR BioGRID; 229396; 1.
DR STRING; 10090.ENSMUSP00000044493; -.
DR iPTMnet; Q149F5; -.
DR PhosphoSitePlus; Q149F5; -.
DR jPOST; Q149F5; -.
DR MaxQB; Q149F5; -.
DR PaxDb; Q149F5; -.
DR PRIDE; Q149F5; -.
DR ProteomicsDB; 259431; -.
DR DNASU; 213068; -.
DR GeneID; 213068; -.
DR KEGG; mmu:213068; -.
DR UCSC; uc007wad.1; mouse.
DR CTD; 137835; -.
DR MGI; MGI:2146049; Tmem71.
DR eggNOG; ENOG502RZWR; Eukaryota.
DR InParanoid; Q149F5; -.
DR OrthoDB; 1207731at2759; -.
DR PhylomeDB; Q149F5; -.
DR TreeFam; TF337383; -.
DR BioGRID-ORCS; 213068; 2 hits in 72 CRISPR screens.
DR ChiTaRS; Tmem71; mouse.
DR PRO; PR:Q149F5; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q149F5; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; ISO:MGI.
DR InterPro; IPR027975; TMEM71.
DR PANTHER; PTHR35255; PTHR35255; 1.
DR Pfam; PF15121; TMEM71; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..287
FT /note="Transmembrane protein 71"
FT /id="PRO_0000278284"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 214
FT /note="V -> D (in Ref. 1; BAC40519/BAE41673)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 287 AA; 31871 MW; D0945C93A41A2004 CRC64;
MYRDSPLMST PVANDSRSDE GPSGKLSPTC LFPSFTCDFL DGDSSFECCS IDPLTGSHYI
CRRSPRLLTN GYYIWTEDSF FCDPDGHITL NPSQTSVMYK ENLVRIFRKK KRTHRSLSSL
LDPRASKSWL HGSIFGEVDS LPSEDLWLDG IRSLGSDLDC SLSDGWESQK PVTDTSESSS
SGYILPQSLR ESSQSSSLQL QVKASGHFEK NSLVHSRAGL MHKVSFQAIL LAVCLVISAY
TRWFVGGELA SIFTCALLIT IAYVVKSLFL NLARYFKATS CARFDST
