ID   TMM80_BOVIN             Reviewed;         143 AA.
AC   A1A4P6;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Transmembrane protein 80;
GN   Name=TMEM80;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Cell projection, cilium
CC       {ECO:0000250|UniProtKB:Q9D3H0}. Note=Localizes at the transition zone,
CC       a region between the basal body and the ciliary axoneme.
CC       {ECO:0000250|UniProtKB:Q9D3H0}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-21 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; BC126790; AAI26791.1; -; mRNA.
DR   RefSeq; NP_001073781.1; NM_001080312.2.
DR   AlphaFoldDB; A1A4P6; -.
DR   STRING; 9913.ENSBTAP00000011892; -.
DR   PaxDb; A1A4P6; -.
DR   Ensembl; ENSBTAT00000011892; ENSBTAP00000011892; ENSBTAG00000009032.
DR   GeneID; 613612; -.
DR   KEGG; bta:613612; -.
DR   CTD; 283232; -.
DR   VEuPathDB; HostDB:ENSBTAG00000009032; -.
DR   VGNC; VGNC:36113; TMEM80.
DR   eggNOG; KOG4502; Eukaryota.
DR   GeneTree; ENSGT00940000153899; -.
DR   HOGENOM; CLU_135948_0_0_1; -.
DR   InParanoid; A1A4P6; -.
DR   OMA; HISECLW; -.
DR   OrthoDB; 1584392at2759; -.
DR   TreeFam; TF323824; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000009032; Expressed in zone of skin and 106 other tissues.
DR   ExpressionAtlas; A1A4P6; baseline.
DR   GO; GO:0035869; C:ciliary transition zone; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:1905515; P:non-motile cilium assembly; IBA:GO_Central.
DR   InterPro; IPR019184; Uncharacterised_TM-17.
DR   PANTHER; PTHR13531; PTHR13531; 1.
DR   Pfam; PF09799; Transmemb_17; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..143
FT                   /note="Transmembrane protein 80"
FT                   /id="PRO_0000287872"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   143 AA;  15339 MW;  A242ACF0C8FC4479 CRC64;
     MAAPRRGKAS STVLSSLPLQ MLLCLSGTYY ALYFLATLLL LVYKSQVFTY PHSCLVLDLT
     LLFLMGILEA IRLYFGTTGN LMEAEVPLAA SLVLTVGSAL LSAYFLLWQT LVLRADSALG
     APLLALHGLE AVLQVVAIAA FVS