AC4_TYLCI
ID AC4_TYLCI Reviewed; 96 AA.
AC P27271;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 23-FEB-2022, entry version 50.
DE RecName: Full=Protein C4;
DE AltName: Full=10.9 kDa protein;
DE AltName: Full=Protein L4;
GN ORFNames=C4, L4;
OS Tomato yellow leaf curl virus (strain Israel) (TYLCV).
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC Geplafuvirales; Geminiviridae; Begomovirus.
OX NCBI_TaxID=66366;
OH NCBI_TaxID=185024; Cynanchum acutum.
OH NCBI_TaxID=145753; Malva parviflora (Little mallow) (Cheeseweed mallow).
OH NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1926771; DOI=10.1016/0042-6822(91)90763-2;
RA Navot N., Pichersky E., Zeidan M., Zamir D., Czosnek H.;
RT "Tomato yellow leaf curl virus: a whitefly-transmitted geminivirus with a
RT single genomic component.";
RL Virology 185:151-161(1991).
RN [2]
RP SUBCELLULAR LOCATION.
RC STRAIN=Isolate Dominican Republic;
RX PubMed=11878881; DOI=10.1006/viro.2001.1194;
RA Rojas M.R., Jiang H., Salati R., Xoconostle-Cazares B., Sudarshana M.R.,
RA Lucas W.J., Gilbertson R.L.;
RT "Functional analysis of proteins involved in movement of the monopartite
RT begomovirus, Tomato yellow leaf curl virus.";
RL Virology 291:110-125(2001).
CC -!- FUNCTION: Pathogenicity determinant (By similarity). May act as a
CC suppressor of RNA-mediated gene silencing, also known as post-
CC transcriptional gene silencing (PTGS), a mechanism of plant viral
CC defense that limits the accumulation of viral RNAs. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Lipid-anchor
CC {ECO:0000250}. Note=Localizes to the cell periphery. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the geminiviridae protein AC4/C4 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA33691.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X15656; CAA33691.1; ALT_INIT; Genomic_DNA.
DR PIR; F40779; QQCVB2.
DR SMR; P27271; -.
DR Proteomes; UP000007547; Genome.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR002488; Gemini_C4.
DR Pfam; PF01492; Gemini_C4; 1.
PE 3: Inferred from homology;
KW Host cell membrane; Host membrane; Lipoprotein; Membrane; Myristate;
KW Reference proteome; Suppressor of RNA silencing.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..96
FT /note="Protein C4"
FT /id="PRO_0000222295"
FT REGION 77..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 2
FT /note="N-myristoyl glycine; by host"
FT /evidence="ECO:0000250"
SQ SEQUENCE 96 AA; 10935 MW; 2CAD38A3EEC87B54 CRC64;
MGNHISMCLS NSKANTNVRT NGSSTWYPQT GQHISIRTFR QLRAQQMSRP TWRKTETSLI
LEFPKSMADQ LEEVSNLPTT HMPKHSIQAV NPRPSI