ID   TMPB_TREPH              Reviewed;         384 AA.
AC   P29720;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Treponemal membrane protein B;
DE   AltName: Full=Antigen TmpB;
DE   Flags: Precursor;
GN   Name=tmpB;
OS   Treponema phagedenis.
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=162;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Kazan 5;
RX   PubMed=1894368; DOI=10.1128/iai.59.10.3685-3693.1991;
RA   Yelton D.B., Limberger R.J., Curci K., Malinosky-Rummell F., Sliviensky L.,
RA   Schouls L.M., van Embden J.D.A., Charon N.W.;
RT   "Treponema phagedenis encodes and expresses homologs of the Treponema
RT   pallidum TmpA and TmpB proteins.";
RL   Infect. Immun. 59:3685-3693(1991).
CC   -!- FUNCTION: Tmp may serve as a porin or transport protein for large
CC       molecules.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: To T.pallidum TmpB. {ECO:0000305}.
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DR   EMBL; M58563; AAA27480.1; -; Genomic_DNA.
DR   PIR; B43592; B43592.
DR   AlphaFoldDB; P29720; -.
DR   SMR; P29720; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Repeat; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..384
FT                   /note="Treponemal membrane protein B"
FT                   /id="PRO_0000022560"
FT   REPEAT          151..155
FT                   /note="1-1"
FT   REPEAT          156..160
FT                   /note="1-2"
FT   REPEAT          161..165
FT                   /note="1-3"
FT   REPEAT          166..170
FT                   /note="1-4"
FT   REPEAT          171..175
FT                   /note="1-5"
FT   REPEAT          176..180
FT                   /note="1-6"
FT   REPEAT          181..185
FT                   /note="1-7"
FT   REPEAT          186..190
FT                   /note="1-8"
FT   REPEAT          191..195
FT                   /note="1-9"
FT   REPEAT          196..200
FT                   /note="1-10"
FT   REPEAT          201..205
FT                   /note="1-11"
FT   REPEAT          206..210
FT                   /note="1-12"
FT   REPEAT          211..215
FT                   /note="1-13"
FT   REPEAT          216..220
FT                   /note="1-14"
FT   REPEAT          221..225
FT                   /note="1-15"
FT   REPEAT          226..230
FT                   /note="1-16"
FT   REPEAT          231..235
FT                   /note="1-17"
FT   REPEAT          236..243
FT                   /note="2-1"
FT   REPEAT          245..252
FT                   /note="2-2"
FT   REPEAT          254..261
FT                   /note="2-3"
FT   REPEAT          263..270
FT                   /note="2-4"
FT   REPEAT          272..279
FT                   /note="2-5"
FT   REPEAT          281..288
FT                   /note="2-6"
FT   REGION          151..235
FT                   /note="17 X 5 AA tandem repeats of K-A-A-[AKR]-[ED]"
FT   REGION          163..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          236..288
FT                   /note="6 X 8 AA tandem repeats of [EA]-A-A-R-X-A-A-E"
SQ   SEQUENCE   384 AA;  42677 MW;  6E94CBC74294DE8C CRC64;
     MKKIFLFLSL VSVLGITSLF AISYDDNEYS RKSRAYTQLA EKAYDAGEYD TAIEYSQLAE
     NFAQESAEYI KRMMARNEAE DAMNKARTRY AWAKQQKADK NYPTEYLIAG EAIKAGGIAF
     DNKNYDVAVT CAEKALESLK TVEPEDKVIA KAAADKAAAE KAAKEKAARE KSAKDKAAKE
     KAAKEKAAKD KAAKEKAAKE KAAKDKAAKE KAAKEKAARE MAAKEKAAKD KAAKEEAARK
     AAEEAAARKA AEEAAARKAA EEEAARIAAE EEAARKAAEE EAARKAAEEA LYNEKGEKVL
     PSEYKVLTWK LDRECFWNIA KNPAVYNDPF MWRKLYEANK DKIPESNNPD WVEAETILVI
     PSIRGERREG LYDPDVKYQA LPKR