ID   AC54_NPVAC              Reviewed;         365 AA.
AC   P41458;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   23-FEB-2022, entry version 42.
DE   RecName: Full=Protein AC54;
GN   Name=AC54; Synonyms=VP1054; ORFNames=ORF54;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [2]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=9188569; DOI=10.1128/jvi.71.7.5040-5050.1997;
RA   Olszewski J., Miller L.K.;
RT   "Identification and characterization of a baculovirus structural protein,
RT   VP1054, required for nucleocapsid formation.";
RL   J. Virol. 71:5040-5050(1997).
RN   [3]
RP   INTERACTION WITH 38K.
RX   PubMed=18922869; DOI=10.1128/jvi.00948-08;
RA   Wu W., Liang H., Kan J., Liu C., Yuan M., Liang C., Yang K., Pang Y.;
RT   "Autographa californica multiple nucleopolyhedrovirus 38K is a novel
RT   nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself.";
RL   J. Virol. 82:12356-12364(2008).
RN   [4]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=23720732; DOI=10.1128/jvi.00068-13;
RA   Marek M., Romier C., Galibert L., Merten O.W., van Oers M.M.;
RT   "Baculovirus VP1054 is an acquired cellular PURalpha, a nucleic acid-
RT   binding protein specific for GGN repeats.";
RL   J. Virol. 87:8465-8480(2013).
RN   [5]
RP   FUNCTION, AND INTERACTION WITH C42 AND VP80.
RX   PubMed=26865720; DOI=10.1128/jvi.02885-15;
RA   Guan Z., Zhong L., Li C., Wu W., Yuan M., Yang K.;
RT   "The Autographa californica Multiple Nucleopolyhedrovirus ac54 gene is
RT   crucial for localization of the major capsid protein VP39 at the site of
RT   nucleocapsid assembly.";
RL   J. Virol. 90:4115-4126(2016).
CC   -!- FUNCTION: Structural protein that participates in nucleocapsid
CC       assembly. Plays an essential role in the proper localization of the
CC       major capsid protein VP39, and the minor capsid protein 38K into the
CC       capsid assembly site. {ECO:0000269|PubMed:23720732,
CC       ECO:0000269|PubMed:26865720, ECO:0000269|PubMed:9188569}.
CC   -!- SUBUNIT: Interacts with C42 and VP80. Interacts with protein 38K.
CC       {ECO:0000269|PubMed:18922869, ECO:0000269|PubMed:26865720}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:23720732,
CC       ECO:0000269|PubMed:9188569}. Note=Present in both the budded virus (BV)
CC       and the occluded virus (OV). The occluded form allows the virus to be
CC       transmitted from insect to insect through ingestion of contaminated
CC       food while the budded form is responsible for the dissemination of
CC       infection throughout the insect host. {ECO:0000269|PubMed:9188569}.
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DR   EMBL; L22858; AAA66684.1; -; Genomic_DNA.
DR   PIR; G72856; G72856.
DR   RefSeq; NP_054084.1; NC_001623.1.
DR   GeneID; 1403887; -.
DR   KEGG; vg:1403887; -.
DR   Proteomes; UP000008292; Genome.
DR   GO; GO:0044423; C:virion component; IDA:UniProtKB.
DR   InterPro; IPR008416; Baculo_VP1054.
DR   Pfam; PF05789; Baculo_VP1054; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Virion.
FT   CHAIN           1..365
FT                   /note="Protein AC54"
FT                   /id="PRO_0000132987"
SQ   SEQUENCE   365 AA;  42094 MW;  CF461E783E0D271F CRC64;
     MCSTKKPIKL DLCASVKLTP FKPMRPPKPM QCWIHPRRAN CKVTRPRNNY SDPDNENDML
     HMTVLNSVFL NEHAKLYYRH LLRNDQAEAR KTILNADSVY ECMLIRPIRT EHFRSVDEAG
     EHNMSVLKII IDAVIKYIGK LADDEYILIA DRMYVDLIYS EFRAIILPQS AYIIKGDYAE
     SDSESGQSVD VCNELEYPWK LITANNCIVS TDESRQSQYI YRTFLLYNTV LTAILKQNNP
     FDVIAENTSI SIIVRNLGSC PNNKDRVKCC DLNYGGVPPG HVMCPPREIT KKFFHYAKWV
     RNPNKYKRYS ELIARQSETG GGSASLRENV NNQLHARDVS QLHLLDWENF MGEFSSYFGL
     HAHNV