ID   AC75_NPVAC              Reviewed;         133 AA.
AC   Q06669;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   29-SEP-2021, entry version 44.
DE   RecName: Full=Protein Ac75;
GN   Name=Ac75; ORFNames=ORF75;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-113.
RC   STRAIN=E2;
RX   PubMed=8126447; DOI=10.1099/0022-1317-75-3-487;
RA   Kool M., Broer R., Zuidema D., Goldbach R.W., Vlak J.M.;
RT   "Nucleotide sequence and genetic organization of a 7.3 kb region (map unit
RT   47 to 52.5) of Autographa californica nuclear polyhedrosis virus fragment
RT   EcoRI-C.";
RL   J. Gen. Virol. 75:487-494(1994).
RN   [3]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=28968422; DOI=10.1371/journal.pone.0185630;
RA   Guo Y.J., Fu S.H., Li L.L.;
RT   "Autographa californica multiple nucleopolyhedrovirus ac75 is required for
RT   egress of nucleocapsids from the nucleus and formation of de novo
RT   intranuclear membrane microvesicles.";
RL   PLoS ONE 12:E0185630-E0185630(2017).
RN   [4]
RP   FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION WITH PROTEIN AC76.
RX   PubMed=29212928; DOI=10.1128/jvi.01509-17;
RA   Shi A., Hu Z., Zuo Y., Wang Y., Wu W., Yuan M., Yang K.;
RT   "Is Required for the Nuclear Egress of Nucleocapsids and Intranuclear
RT   Microvesicle Formation.";
RL   J. Virol. 92:0-0(2018).
CC   -!- FUNCTION: Plays a role in nuclear egress of nucleocapsids and
CC       intranuclear microvesicle formation. {ECO:0000269|PubMed:29212928,
CC       ECO:0000269|PubMed:8126447}.
CC   -!- SUBUNIT: Interacts with protein Ac76. {ECO:0000269|PubMed:29212928}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:28968422,
CC       ECO:0000269|PubMed:29212928}. Host cytoplasm
CC       {ECO:0000269|PubMed:28968422, ECO:0000269|PubMed:29212928}. Host
CC       nucleus {ECO:0000269|PubMed:28968422, ECO:0000269|PubMed:29212928}.
CC       Note=Localizes predominantly in the host intranuclear rim, site of
CC       several morphogenetic processes associated with occlusion-derived
CC       virions (ODV). {ECO:0000269|PubMed:29212928}.
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DR   EMBL; L22858; AAA66705.1; -; Genomic_DNA.
DR   EMBL; X71415; CAA50538.1; -; Genomic_DNA.
DR   PIR; D72859; D72859.
DR   RefSeq; NP_054105.1; NC_001623.1.
DR   GeneID; 1403908; -.
DR   KEGG; vg:1403908; -.
DR   Proteomes; UP000008292; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IDA:UniProtKB.
DR   GO; GO:0042025; C:host cell nucleus; IDA:UniProtKB.
DR   GO; GO:0044423; C:virion component; IDA:UniProtKB.
DR   GO; GO:0046802; P:exit of virus from host cell nucleus by nuclear egress; IDA:UniProtKB.
DR   InterPro; IPR010594; AcMNPV_Ac75.
DR   Pfam; PF06648; DUF1160; 1.
PE   1: Evidence at protein level;
KW   Host cytoplasm; Host nucleus; Reference proteome; Virion.
FT   CHAIN           1..133
FT                   /note="Protein Ac75"
FT                   /id="PRO_0000133016"
SQ   SEQUENCE   133 AA;  15512 MW;  8AEF01EFD2986F35 CRC64;
     MSNLMKNFFT ELVKSTTFTT KVSVVKTTLS NWLCEQVYPD KDFSLKLKRV VNMFLNNEIE
     NNKIYKLVET VDSSNKLSRR QVDFLIHALL NNVSVTFTLH RFVDDNVLTQ DELSFLANFL
     VTKMDEAYQL PAY