ID   TNNI2_COTJA             Reviewed;         183 AA.
AC   P68247; P02644;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Troponin I, fast skeletal muscle;
DE   AltName: Full=Troponin I, fast-twitch isoform;
GN   Name=TNNI2;
OS   Coturnix japonica (Japanese quail) (Coturnix coturnix japonica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Perdicinae; Coturnix.
OX   NCBI_TaxID=93934;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3865218; DOI=10.1073/pnas.82.23.8080;
RA   Baldwin A.S. Jr., Kittler E.L.W., Emerson C.P. Jr.;
RT   "Structure, evolution, and regulation of a fast skeletal muscle troponin I
RT   gene.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:8080-8084(1985).
CC   -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC       filament regulatory complex which confers calcium-sensitivity to
CC       striated muscle actomyosin ATPase activity.
CC   -!- SUBUNIT: Binds to actin and tropomyosin.
CC   -!- PTM: The N-terminus is blocked.
CC   -!- SIMILARITY: Belongs to the troponin I family. {ECO:0000305}.
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DR   EMBL; M12132; AAB00122.1; -; Genomic_DNA.
DR   PIR; A23569; A23569.
DR   AlphaFoldDB; P68247; -.
DR   BMRB; P68247; -.
DR   SMR; P68247; -.
DR   Proteomes; UP000694412; Unplaced.
DR   GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.350; -; 1.
DR   InterPro; IPR001978; Troponin.
DR   InterPro; IPR038077; Troponin_sf.
DR   Pfam; PF00992; Troponin; 1.
DR   SUPFAM; SSF90250; SSF90250; 1.
PE   3: Inferred from homology;
KW   Acetylation; Actin-binding; Muscle protein; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..183
FT                   /note="Troponin I, fast skeletal muscle"
FT                   /id="PRO_0000186148"
FT   REGION          2..48
FT                   /note="Involved in binding TNC"
FT   REGION          97..117
FT                   /note="Involved in binding TNC and actin"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   183 AA;  21234 MW;  E33F7517E84BB09E CRC64;
     MSDEEKKRRA ATARRQHLKS AMLQLAVTEI EKEAAAKEVE KQNYLAEHCP PLSLPGSMQE
     LQELCKKLHA KIDSVDEERY DTEVKLQKTN KELEDLSQKL FDLRGKFKRP PLRRVRMSAD
     AMLRALLGSK HKVNMDLRAN LKQVKKEDTE KEKDLRDVGD WRKNIEEKSG MEGRKKMFEA
     GES