ID   BTG1_CHICK              Reviewed;         170 AA.
AC   P34743;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Protein BTG1;
DE   AltName: Full=B-cell translocation gene 1 protein;
GN   Name=BTG1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8325512; DOI=10.1016/0378-1119(93)90284-a;
RA   Rouault J.-P., Samarut C., Duret L., Tessa C., Samarut J., Magaud J.-P.;
RT   "Sequence analysis reveals that the BTG1 anti-proliferative gene is
RT   conserved throughout evolution in its coding and 3' non-coding regions.";
RL   Gene 129:303-306(1993).
CC   -!- FUNCTION: Anti-proliferative protein.
CC   -!- DEVELOPMENTAL STAGE: Its expression is associated with the early G1
CC       phase of the cell cycle.
CC   -!- SIMILARITY: Belongs to the BTG family. {ECO:0000305}.
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DR   EMBL; X64146; CAA45507.1; -; mRNA.
DR   PIR; I50585; S19961.
DR   RefSeq; NP_990681.1; NM_205350.1.
DR   AlphaFoldDB; P34743; -.
DR   SMR; P34743; -.
DR   STRING; 9031.ENSGALP00000018378; -.
DR   PaxDb; P34743; -.
DR   GeneID; 396295; -.
DR   KEGG; gga:396295; -.
DR   CTD; 694; -.
DR   VEuPathDB; HostDB:geneid_396295; -.
DR   eggNOG; KOG4006; Eukaryota.
DR   HOGENOM; CLU_079660_4_0_1; -.
DR   InParanoid; P34743; -.
DR   OrthoDB; 1439942at2759; -.
DR   PhylomeDB; P34743; -.
DR   TreeFam; TF105272; -.
DR   PRO; PR:P34743; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IBA:GO_Central.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; ISS:UniProtKB.
DR   Gene3D; 3.90.640.90; -; 1.
DR   InterPro; IPR002087; Anti_prolifrtn.
DR   InterPro; IPR033332; BTG.
DR   InterPro; IPR036054; BTG-like_sf.
DR   InterPro; IPR033330; BTG1.
DR   PANTHER; PTHR22978; PTHR22978; 1.
DR   PANTHER; PTHR22978:SF30; PTHR22978:SF30; 1.
DR   Pfam; PF07742; BTG; 1.
DR   PRINTS; PR00310; ANTIPRLFBTG1.
DR   SMART; SM00099; btg1; 1.
DR   SUPFAM; SSF160696; SSF160696; 1.
DR   PROSITE; PS00960; BTG_1; 1.
DR   PROSITE; PS01203; BTG_2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..170
FT                   /note="Protein BTG1"
FT                   /id="PRO_0000143803"
SQ   SEQUENCE   170 AA;  19188 MW;  BA4BA1BFCBCEA2B4 CRC64;
     MHPALYTRAS MIREIAAAVA FISKFLRTKG LMNERQLQTF SQSLQELLAE HYKHHWFPEK
     PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFQLLPS ELTLWVDPYE VSYRIGEDGS
     ICVLYEAAPA GGSQNNTNMQ MVDSRISCKE ELLLGRTSPS KSYNMMTVSG