BTG1_RAT
ID BTG1_RAT Reviewed; 171 AA.
AC Q63073;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Protein BTG1;
DE AltName: Full=Anti-proliferative factor;
DE AltName: Full=B-cell translocation gene 1 protein;
GN Name=Btg1;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Sprague-Dawley; TISSUE=Testis;
RX PubMed=7588335; DOI=10.1210/endo.136.12.7588335;
RA Raburn D.J., Hamil K.G., Tsuruta J.K., O'Brien D.A., Hall S.H.;
RT "Stage-specific expression of B cell translocation gene 1 in rat testis.";
RL Endocrinology 136:5769-5777(1995).
CC -!- FUNCTION: Anti-proliferative protein.
CC -!- SUBUNIT: Interacts with CNOT7 and CNOT8. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BTG family. {ECO:0000305}.
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DR EMBL; L26268; AAA85779.1; -; mRNA.
DR RefSeq; NP_058954.1; NM_017258.1.
DR AlphaFoldDB; Q63073; -.
DR SMR; Q63073; -.
DR IntAct; Q63073; 1.
DR STRING; 10116.ENSRNOP00000005910; -.
DR PaxDb; Q63073; -.
DR Ensembl; ENSRNOT00000005910; ENSRNOP00000005910; ENSRNOG00000004284.
DR GeneID; 29618; -.
DR KEGG; rno:29618; -.
DR UCSC; RGD:2224; rat.
DR CTD; 694; -.
DR RGD; 2224; Btg1.
DR eggNOG; KOG4006; Eukaryota.
DR GeneTree; ENSGT00950000182952; -.
DR HOGENOM; CLU_079660_4_0_1; -.
DR InParanoid; Q63073; -.
DR OMA; YNNMMTV; -.
DR OrthoDB; 1439942at2759; -.
DR PhylomeDB; Q63073; -.
DR TreeFam; TF105272; -.
DR PRO; PR:Q63073; -.
DR Proteomes; UP000002494; Chromosome 7.
DR Bgee; ENSRNOG00000004284; Expressed in thymus and 20 other tissues.
DR Genevisible; Q63073; RN.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:RGD.
DR GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR GO; GO:0008283; P:cell population proliferation; IEA:Ensembl.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR GO; GO:0045603; P:positive regulation of endothelial cell differentiation; ISS:UniProtKB.
DR GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; ISS:UniProtKB.
DR GO; GO:0045663; P:positive regulation of myoblast differentiation; ISO:RGD.
DR GO; GO:0006479; P:protein methylation; ISO:RGD.
DR GO; GO:0006979; P:response to oxidative stress; IEP:RGD.
DR GO; GO:0043434; P:response to peptide hormone; IEP:RGD.
DR GO; GO:0007286; P:spermatid development; NAS:UniProtKB.
DR GO; GO:0007283; P:spermatogenesis; IEP:RGD.
DR Gene3D; 3.90.640.90; -; 1.
DR InterPro; IPR002087; Anti_prolifrtn.
DR InterPro; IPR033332; BTG.
DR InterPro; IPR036054; BTG-like_sf.
DR InterPro; IPR033330; BTG1.
DR PANTHER; PTHR22978; PTHR22978; 1.
DR PANTHER; PTHR22978:SF30; PTHR22978:SF30; 1.
DR Pfam; PF07742; BTG; 1.
DR PRINTS; PR00310; ANTIPRLFBTG1.
DR SMART; SM00099; btg1; 1.
DR SUPFAM; SSF160696; SSF160696; 1.
DR PROSITE; PS00960; BTG_1; 1.
DR PROSITE; PS01203; BTG_2; 1.
PE 2: Evidence at transcript level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..171
FT /note="Protein BTG1"
FT /id="PRO_0000143802"
FT MOD_RES 159
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P62324"
SQ SEQUENCE 171 AA; 19195 MW; F4ED8BE09017EF25 CRC64;
MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE HYKHHWFPEK
PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS ELTLWVDPYE VSYRIGEDGS
ICVLYEASPA GGSSQNSTNV QMVDSRISCK EELLLGRTSP SKNYNMMTVS G
