BTG3_PIG
ID BTG3_PIG Reviewed; 252 AA.
AC A4UTQ2;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Protein BTG3;
DE AltName: Full=BTG family member 3;
GN Name=BTG3;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Muscle;
RA Zhao S., Feng Z., Li K.;
RT "Molecular characterization of the BTG2 and BTG3 genes in fetal muscle
RT development of lean and fatty pig breeds.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Overexpression impairs serum-induced cell cycle progression
CC from the G0/G1 to S phase. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BTG family. {ECO:0000305}.
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DR EMBL; EF486868; ABP01569.1; -; mRNA.
DR RefSeq; NP_001090986.1; NM_001097517.1.
DR AlphaFoldDB; A4UTQ2; -.
DR SMR; A4UTQ2; -.
DR STRING; 9823.ENSSSCP00000012797; -.
DR PaxDb; A4UTQ2; -.
DR PRIDE; A4UTQ2; -.
DR Ensembl; ENSSSCT00000077168; ENSSSCP00000069605; ENSSSCG00000012014.
DR Ensembl; ENSSSCT00005049381; ENSSSCP00005030485; ENSSSCG00005030921.
DR Ensembl; ENSSSCT00015021949; ENSSSCP00015008600; ENSSSCG00015016572.
DR Ensembl; ENSSSCT00025007089; ENSSSCP00025002906; ENSSSCG00025005270.
DR Ensembl; ENSSSCT00030044676; ENSSSCP00030020081; ENSSSCG00030032294.
DR Ensembl; ENSSSCT00035089489; ENSSSCP00035037407; ENSSSCG00035066423.
DR Ensembl; ENSSSCT00040088684; ENSSSCP00040038983; ENSSSCG00040064866.
DR Ensembl; ENSSSCT00045055455; ENSSSCP00045038668; ENSSSCG00045032456.
DR Ensembl; ENSSSCT00050053542; ENSSSCP00050022504; ENSSSCG00050039666.
DR Ensembl; ENSSSCT00055018734; ENSSSCP00055014765; ENSSSCG00055009573.
DR Ensembl; ENSSSCT00060105141; ENSSSCP00060046147; ENSSSCG00060076568.
DR Ensembl; ENSSSCT00065034115; ENSSSCP00065014122; ENSSSCG00065025497.
DR Ensembl; ENSSSCT00070033318; ENSSSCP00070027829; ENSSSCG00070016918.
DR GeneID; 100048957; -.
DR KEGG; ssc:100048957; -.
DR CTD; 10950; -.
DR VGNC; VGNC:103908; BTG3.
DR eggNOG; KOG4006; Eukaryota.
DR GeneTree; ENSGT00950000182952; -.
DR HOGENOM; CLU_079660_3_0_1; -.
DR InParanoid; A4UTQ2; -.
DR OMA; HYGYRPR; -.
DR OrthoDB; 1455216at2759; -.
DR TreeFam; TF105272; -.
DR Proteomes; UP000008227; Chromosome 13.
DR Proteomes; UP000314985; Chromosome 13.
DR Bgee; ENSSSCG00000012014; Expressed in stomach and 46 other tissues.
DR ExpressionAtlas; A4UTQ2; baseline and differential.
DR Genevisible; A4UTQ2; SS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IBA:GO_Central.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IBA:GO_Central.
DR Gene3D; 3.90.640.90; -; 1.
DR InterPro; IPR002087; Anti_prolifrtn.
DR InterPro; IPR033332; BTG.
DR InterPro; IPR036054; BTG-like_sf.
DR PANTHER; PTHR22978; PTHR22978; 1.
DR Pfam; PF07742; BTG; 1.
DR PRINTS; PR00310; ANTIPRLFBTG1.
DR SMART; SM00099; btg1; 1.
DR SUPFAM; SSF160696; SSF160696; 1.
DR PROSITE; PS00960; BTG_1; 1.
DR PROSITE; PS01203; BTG_2; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..252
FT /note="Protein BTG3"
FT /id="PRO_0000289656"
FT REGION 138..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 252 AA; 29154 MW; 41481B74F5A80F3C CRC64;
MKNEIAAVVF FFTRLVRKHD KLKKEAVERF AEKLTLILQE KYKNHWYPEK PSKGQAYRCI
RVNKFQRVDP DVLKACENSC ILYSDLGLPK ELTLWVDPCE VCCRYGEKNN AFIVASFENE
EENKDEISKK VTRALDKVTS DYHSGSSSSD EETSKEVEVK PNSVTATPSP VYQISELIFP
PLPMWHPLPR KKPGMYRGNG HQNHYPPPVP FGYPNQGRKN KPYRPIPVTW VPPPGMHCDR
NHWINPHMLA PH