ID   TNR5_PSEAI              Reviewed;         186 AA.
AC   P06691;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Transposon Tn501 resolvase;
GN   Name=tnpR;
OS   Pseudomonas aeruginosa.
OG   Plasmid pVS1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6312271; DOI=10.1007/bf00334812;
RA   Diver W.P., Grinsted J., Fritzinger D.C., Brown N.L., Altenbuchner J.,
RA   Rogowsky P., Schmitt R.;
RT   "DNA sequences of and complementation by the tnpR genes of Tn21, Tn501 and
RT   Tn1721.";
RL   Mol. Gen. Genet. 191:189-193(1983).
CC   -!- FUNCTION: Resolvase catalyzes the resolution (a site-specific
CC       recombination) of the cointegrated replicon to yield the final
CC       transposition products.
CC   -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC       {ECO:0000305}.
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DR   EMBL; Z00027; CAA77327.1; -; Genomic_DNA.
DR   PIR; S09632; S09632.
DR   RefSeq; WP_010921730.1; NZ_VMNR01000049.1.
DR   AlphaFoldDB; P06691; -.
DR   SMR; P06691; -.
DR   eggNOG; COG1961; Bacteria.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006118; Recombinase_CS.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   InterPro; IPR006120; Resolvase_HTH_dom.
DR   Pfam; PF02796; HTH_7; 1.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS00397; RECOMBINASES_1; 1.
DR   PROSITE; PS00398; RECOMBINASES_2; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Plasmid;
KW   Transposable element.
FT   CHAIN           1..186
FT                   /note="Transposon Tn501 resolvase"
FT                   /id="PRO_0000196373"
FT   DOMAIN          4..137
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   DNA_BIND        164..183
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   REGION          17..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        12
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   186 AA;  21317 MW;  E7F367ED36580A6A CRC64;
     MQGHRIGYVR VSSFDQNPER QLEQTQVSKV FTDKASGKDT QRPQLEALLS FVREGDTVVV
     HSMDRLARNL DDLRRLVQKL TQRGVRIEFL KEGLVFTGED SPMANLMLSV MGAFAEFERA
     LIRERQREGI TLAKQRGAYR GRKKALSDEQ AATLRQRATA GEPKAQLARE FNISRETLYQ
     YLRTDD