ID   TNR7_ECOLX              Reviewed;         186 AA.
AC   P0C1G2; P06692; P71417;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Transposons Tn1721 resolvase;
GN   Name=tnpR;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TRANSPOSON=Tn1721;
RX   PubMed=2993811; DOI=10.1007/bf00383332;
RA   Rogowsky P., Schmitt R.;
RT   "Tn1721-encoded resolvase: structure of the tnpR gene and its in vitro
RT   functions.";
RL   Mol. Gen. Genet. 200:176-181(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TRANSPOSON=Tn1721;
RX   PubMed=1312499; DOI=10.1016/0378-1119(92)90597-i;
RA   Allmeier H., Cresnar B., Greck M., Schmitt R.;
RT   "Complete nucleotide sequence of Tn1721: gene organization and a novel gene
RT   product with features of a chemotaxis protein.";
RL   Gene 111:11-20(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-27.
RC   TRANSPOSON=Tn1721;
RX   PubMed=6312271; DOI=10.1007/bf00334812;
RA   Diver W.P., Grinsted J., Fritzinger D.C., Brown N.L., Altenbuchner J.,
RA   Rogowsky P., Schmitt R.;
RT   "DNA sequences of and complementation by the tnpR genes of Tn21, Tn501 and
RT   Tn1721.";
RL   Mol. Gen. Genet. 191:189-193(1983).
CC   -!- FUNCTION: Resolvase catalyzes the resolution (a site-specific
CC       recombination) of the cointegrated replicon to yield the final
CC       transposition products.
CC   -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC       {ECO:0000305}.
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DR   EMBL; X02590; CAA26430.1; -; Genomic_DNA.
DR   EMBL; X61367; CAA43640.1; -; Genomic_DNA.
DR   EMBL; X01299; CAA25628.1; -; Genomic_DNA.
DR   PIR; B32806; B32806.
DR   RefSeq; WP_001161490.1; NZ_WVVT01000032.1.
DR   RefSeq; YP_006952171.1; NC_019056.1.
DR   RefSeq; YP_006952402.1; NC_019062.1.
DR   RefSeq; YP_009061542.1; NC_024979.1.
DR   RefSeq; YP_009068486.1; NC_025141.1.
DR   RefSeq; YP_009068725.1; NC_025142.1.
DR   RefSeq; YP_009068861.1; NC_025143.1.
DR   RefSeq; YP_009069129.1; NC_025144.1.
DR   RefSeq; YP_009070867.1; NC_025176.1.
DR   RefSeq; YP_190209.1; NC_006671.1.
DR   AlphaFoldDB; P0C1G2; -.
DR   SMR; P0C1G2; -.
DR   GeneID; 58463196; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006118; Recombinase_CS.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   InterPro; IPR006120; Resolvase_HTH_dom.
DR   Pfam; PF02796; HTH_7; 1.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS00397; RECOMBINASES_1; 1.
DR   PROSITE; PS00398; RECOMBINASES_2; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Transposable element.
FT   CHAIN           1..186
FT                   /note="Transposons Tn1721 resolvase"
FT                   /id="PRO_0000196376"
FT   DOMAIN          4..137
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   DNA_BIND        164..183
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        12
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   186 AA;  21287 MW;  12F372F836580A70 CRC64;
     MQGHRIGYVR VSSFDQNPER QLEQTQVSKV FTDKASGKDT QRPQLEALLS FVREGDTVVV
     HSMDRLARNL DDLRRLVQKL TQRGVRIEFL KEGLVFTGED SPMANLMLSV MGAFAEFERA
     LIRERQREGI ALAKQRGAYR GRKKALSDEQ AATLRQRATA GEPKAQLARE FNISRETLYQ
     YLRTDD