TNT_HUMAN
ID TNT_HUMAN Reviewed; 217 AA.
AC Q7Z2V1; B9EGC2; Q8NEF0;
DT 15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Protein TNT;
GN Name=C16orf82;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Teratocarcinoma;
RA Guo J.H., Yu L.;
RL Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- TISSUE SPECIFICITY: Preferentially expressed in teratocarcinoma rather
CC than in normal testis.
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DR EMBL; AF536240; AAP97728.1; -; mRNA.
DR EMBL; AC092725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471145; EAW55761.1; -; Genomic_DNA.
DR EMBL; BC031257; AAH31257.1; -; mRNA.
DR EMBL; BC136370; AAI36371.1; -; mRNA.
DR EMBL; BC136382; AAI36383.1; -; mRNA.
DR RefSeq; NP_001139017.1; NM_001145545.1.
DR AlphaFoldDB; Q7Z2V1; -.
DR iPTMnet; Q7Z2V1; -.
DR PhosphoSitePlus; Q7Z2V1; -.
DR BioMuta; C16orf82; -.
DR MassIVE; Q7Z2V1; -.
DR PeptideAtlas; Q7Z2V1; -.
DR PRIDE; Q7Z2V1; -.
DR DNASU; 162083; -.
DR GeneID; 162083; -.
DR KEGG; hsa:162083; -.
DR CTD; 162083; -.
DR DisGeNET; 162083; -.
DR GeneCards; C16orf82; -.
DR HGNC; HGNC:30755; C16orf82.
DR neXtProt; NX_Q7Z2V1; -.
DR PharmGKB; PA164716846; -.
DR InParanoid; Q7Z2V1; -.
DR OrthoDB; 1535203at2759; -.
DR PhylomeDB; Q7Z2V1; -.
DR PathwayCommons; Q7Z2V1; -.
DR BioGRID-ORCS; 162083; 1 hit in 123 CRISPR screens.
DR ChiTaRS; C16orf82; human.
DR GenomeRNAi; 162083; -.
DR Pharos; Q7Z2V1; Tdark.
DR PRO; PR:Q7Z2V1; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q7Z2V1; protein.
DR InterPro; IPR031520; DUF4694.
DR PANTHER; PTHR40139; PTHR40139; 1.
DR Pfam; PF15765; DUF4694; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..217
FT /note="Protein TNT"
FT /id="PRO_0000072616"
FT REGION 1..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 217 AA; 23111 MW; 93E786B9C2F6EC83 CRC64;
MSLVPGQHCS PSHTRLHLTS PITMGTEPAT QNTEFSKGSL IYGVTSPQRG HSQHSEASQG
PLSLDKPLQL PPIFLEGEKG ESSVQNEQEG EPSLQSPSLE LQSPAWPRHA GVAQEPLKVS
SSYLSDTQSS ESHVSSVQHP RPEEGSHASL SSGYAGDKEG SDISLVGSHR RVRLNRRLNT
QAASNQTSQL GSIDPPSSLK SRLTGPAHST KQTGGKE
