TO20L_MOUSE
ID TO20L_MOUSE Reviewed; 152 AA.
AC Q9D4V6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=TOMM20-like protein 1;
GN Name=Tomm20l;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000305};
CC Single-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the Tom20 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK016101; BAB30114.1; -; mRNA.
DR CCDS; CCDS49080.1; -.
DR RefSeq; NP_083503.1; NM_029227.1.
DR AlphaFoldDB; Q9D4V6; -.
DR SMR; Q9D4V6; -.
DR STRING; 10090.ENSMUSP00000021482; -.
DR PaxDb; Q9D4V6; -.
DR PRIDE; Q9D4V6; -.
DR ProteomicsDB; 260646; -.
DR Antibodypedia; 51460; 66 antibodies from 14 providers.
DR Ensembl; ENSMUST00000021482; ENSMUSP00000021482; ENSMUSG00000021078.
DR GeneID; 75266; -.
DR KEGG; mmu:75266; -.
DR UCSC; uc007nug.1; mouse.
DR CTD; 387990; -.
DR MGI; MGI:1922516; Tomm20l.
DR VEuPathDB; HostDB:ENSMUSG00000021078; -.
DR eggNOG; KOG4056; Eukaryota.
DR GeneTree; ENSGT00390000011698; -.
DR HOGENOM; CLU_100000_2_0_1; -.
DR InParanoid; Q9D4V6; -.
DR OMA; AIMICAD; -.
DR OrthoDB; 1316067at2759; -.
DR PhylomeDB; Q9D4V6; -.
DR TreeFam; TF106200; -.
DR BioGRID-ORCS; 75266; 0 hits in 72 CRISPR screens.
DR PRO; PR:Q9D4V6; -.
DR Proteomes; UP000000589; Chromosome 12.
DR RNAct; Q9D4V6; protein.
DR Bgee; ENSMUSG00000021078; Expressed in spermatid and 23 other tissues.
DR ExpressionAtlas; Q9D4V6; baseline and differential.
DR Genevisible; Q9D4V6; MM.
DR GO; GO:0031307; C:integral component of mitochondrial outer membrane; IBA:GO_Central.
DR GO; GO:0005742; C:mitochondrial outer membrane translocase complex; IBA:GO_Central.
DR GO; GO:0030943; F:mitochondrion targeting sequence binding; IBA:GO_Central.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0016031; P:tRNA import into mitochondrion; IBA:GO_Central.
DR Gene3D; 1.20.960.10; -; 1.
DR InterPro; IPR002056; MAS20.
DR InterPro; IPR022422; MAS20_rcpt_metazoan.
DR InterPro; IPR023392; Tom20_dom_sf.
DR PANTHER; PTHR12430; PTHR12430; 1.
DR Pfam; PF02064; MAS20; 1.
DR PIRSF; PIRSF037707; MAS20_rcpt; 1.
DR PRINTS; PR01989; EUOM20RECPTR.
DR PRINTS; PR00351; OM20RECEPTOR.
DR SUPFAM; SSF47157; SSF47157; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..152
FT /note="TOMM20-like protein 1"
FT /id="PRO_0000317748"
FT TOPO_DOM 1..6
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 28..152
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 152 AA; 17580 MW; 0314963787A95F73 CRC64;
MPSVRLGVGL LAGLAAGGAV VLLSYCVYLD WRRHRDPAFR RRLQDKRRAG QPKAQAPARQ
LWDPVKKEEL QEYFFREVQM GKLCLIRGER GMGFEHLTNA LLVCEQPKEL LMFFKKTLPP
EVFQMLLDKI PLICQQLEET CRSTEHLKDD PD
