TOCC_ORYSJ
ID TOCC_ORYSJ Reviewed; 470 AA.
AC Q6K7V6; A0A0P0VHH9; Q6K7V5;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Probable tocopherol cyclase, chloroplastic;
DE AltName: Full=Vitamin E pathway gene 1 protein;
DE Flags: Precursor;
GN Name=VTE1; OrderedLocusNames=Os02g0276500, LOC_Os02g17650;
GN ORFNames=OsJ_06237, OSJNBa0055M07.5, P0017G06.29;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RC STRAIN=cv. Taipei 309;
RX PubMed=21318489; DOI=10.1007/s11427-011-4138-1;
RA Ouyang S., He S., Liu P., Zhang W., Zhang J., Chen S.;
RT "The role of tocopherol cyclase in salt stress tolerance of rice (Oryza
RT sativa).";
RL Sci. China Life Sci. 54:181-188(2011).
CC -!- FUNCTION: Involved in the synthesis of both tocopherols and
CC tocotrienols (vitamin E), which presumably protect photosynthetic
CC complexes from oxidative stress. Catalyzes the conversion of 2-methyl-
CC 6-phytyl-1,4-hydroquinone and 2,3-dimethyl-5-phytyl-1,4-hydroquinone
CC (DMPQ) to delta- and gamma-tocopherol respectively. Converts also 2,3-
CC dimethyl-5-geranylgeranyl-1,4-hydroquinone (DMGQ) to gamma-tocotrienol
CC (By similarity). {ECO:0000250, ECO:0000269|PubMed:21318489}.
CC -!- PATHWAY: Cofactor biosynthesis; tocopherol biosynthesis.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast, plastoglobule
CC {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in the roots, stems, leaves and
CC spikelets. {ECO:0000269|PubMed:21318489}.
CC -!- INDUCTION: By salt and drougt stresses, H(2)O(2), salicylic acid (SA)
CC and abscisic acid (ABA). {ECO:0000269|PubMed:21318489}.
CC -!- MISCELLANEOUS: Plants overexpressing VTE1 show increased tolerance to
CC salt stress with reduced H(2)O(2) levels. Plants silencing VTE1 show
CC enhanced sensitivity to salt stress with increased H(2)O(2) levels.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD21817.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD28674.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP004770; BAD21816.1; -; Genomic_DNA.
DR EMBL; AP004770; BAD21817.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005536; BAD28673.1; -; Genomic_DNA.
DR EMBL; AP005536; BAD28674.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAF08459.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS78094.1; -; Genomic_DNA.
DR EMBL; CM000139; EEE56731.1; -; Genomic_DNA.
DR EMBL; AK072052; BAG92802.1; -; mRNA.
DR RefSeq; XP_015626329.1; XM_015770843.1.
DR AlphaFoldDB; Q6K7V6; -.
DR STRING; 4530.OS02T0276500-01; -.
DR PaxDb; Q6K7V6; -.
DR PRIDE; Q6K7V6; -.
DR EnsemblPlants; Os02t0276500-01; Os02t0276500-01; Os02g0276500.
DR GeneID; 4329007; -.
DR Gramene; Os02t0276500-01; Os02t0276500-01; Os02g0276500.
DR KEGG; osa:4329007; -.
DR eggNOG; ENOG502QQ9P; Eukaryota.
DR HOGENOM; CLU_048962_0_0_1; -.
DR InParanoid; Q6K7V6; -.
DR OMA; FAFMYSI; -.
DR OrthoDB; 1312305at2759; -.
DR PlantReactome; R-OSA-1119287; Vitamin E biosynthesis.
DR UniPathway; UPA00160; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6K7V6; OS.
DR GO; GO:0010287; C:plastoglobule; IEA:UniProtKB-SubCell.
DR GO; GO:0009976; F:tocopherol cyclase activity; IEA:InterPro.
DR GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR GO; GO:0009651; P:response to salt stress; IMP:UniProtKB.
DR GO; GO:0010189; P:vitamin E biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR025893; Tocopherol_cyclase.
DR PANTHER; PTHR35309; PTHR35309; 1.
DR Pfam; PF14249; Tocopherol_cycl; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..61
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 62..470
FT /note="Probable tocopherol cyclase, chloroplastic"
FT /id="PRO_0000409872"
FT REGION 14..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 52195 MW; 0E354ED483BB3003 CRC64;
MDLAAAAVAV SFPRPAPPPR RCAPRRHRRA LAPRAASSSP SPSTAVAAPV YAPTPRDRAL
RTPHSGYHYD GTARPFFEGW YFKVSIPECR QSFCFMYSVE NPLFRDGMSD LDRVIHGSRF
TGVGAQILGA DDKYICQFTE KSNNFWGSRH ELMLGNTFIP NNGSTPPEGE VPPQEFSSRV
LEGFQVTPIW HQGFIRDDGR SKYVPNVQTA RWEYSTRPVY GWGDVTSKQK STAGWLAAFP
FFEPHWQICM AGGLSTGWIE WDGERFEFEN APSYSEKNWG AGFPRKWYWV QCNVFSGASG
EVALTAAGGL RKIGLGETYE SPSLIGIHYE GKFYEFVPWT GTVSWDIAPW GHWKLSGENK
NHLVEIEATT KEPGTALRAP TMEAGLVPAC KDTCYGDLRL QMWEKRNDGG KGKMILDATS
NMAALEVGGG PWFNGWKGTT VSNEIVNNVV GTQVDVESLF PIPFLKPPGL
