TOE3_ARATH
ID TOE3_ARATH Reviewed; 352 AA.
AC Q9FH95;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=AP2-like ethylene-responsive transcription factor TOE3;
DE AltName: Full=Protein TARGET OF EAT 3;
GN Name=TOE3; OrderedLocusNames=At5g67180; ORFNames=K21H1.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION.
RX PubMed=15988559; DOI=10.1007/s11103-005-0955-6;
RA Nole-Wilson S., Tranby T.L., Krizek B.A.;
RT "AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may
RT specify meristematic or division-competent states.";
RL Plant Mol. Biol. 57:613-628(2005).
RN [7]
RP FUNCTION, AND INDUCTION.
RX PubMed=14555699; DOI=10.1105/tpc.016238;
RA Aukerman M.J., Sakai H.;
RT "Regulation of flowering time and floral organ identity by a microRNA and
RT its APETALA2-like target genes.";
RL Plant Cell 15:2730-2741(2003).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). May regulate
CC negatively the transition to flowering time and confers flowering time
CC delay. {ECO:0000250, ECO:0000269|PubMed:14555699,
CC ECO:0000269|PubMed:15988559}.
CC -!- INTERACTION:
CC Q9FH95; Q93Z00: TCP14; NbExp=4; IntAct=EBI-15202554, EBI-4424563;
CC Q9FH95; Q8LPR5: TCP4; NbExp=3; IntAct=EBI-15202554, EBI-15192325;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- INDUCTION: Repressed by miR172a-2/EAT. {ECO:0000269|PubMed:14555699}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB020742; BAB10952.1; -; Genomic_DNA.
DR EMBL; CP002688; AED98311.1; -; Genomic_DNA.
DR EMBL; AK176145; BAD43908.1; -; mRNA.
DR EMBL; BT029206; ABJ17141.1; -; mRNA.
DR EMBL; AY088238; AAM65779.1; -; mRNA.
DR RefSeq; NP_201519.1; NM_126118.4.
DR AlphaFoldDB; Q9FH95; -.
DR SMR; Q9FH95; -.
DR BioGRID; 22095; 16.
DR IntAct; Q9FH95; 14.
DR STRING; 3702.AT5G67180.1; -.
DR PaxDb; Q9FH95; -.
DR PRIDE; Q9FH95; -.
DR ProteomicsDB; 234361; -.
DR EnsemblPlants; AT5G67180.1; AT5G67180.1; AT5G67180.
DR GeneID; 836853; -.
DR Gramene; AT5G67180.1; AT5G67180.1; AT5G67180.
DR KEGG; ath:AT5G67180; -.
DR Araport; AT5G67180; -.
DR TAIR; locus:2155598; AT5G67180.
DR eggNOG; ENOG502QQXB; Eukaryota.
DR HOGENOM; CLU_035462_4_0_1; -.
DR OrthoDB; 1171664at2759; -.
DR PhylomeDB; Q9FH95; -.
DR PRO; PR:Q9FH95; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FH95; baseline and differential.
DR Genevisible; Q9FH95; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 2.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..352
FT /note="AP2-like ethylene-responsive transcription factor
FT TOE3"
FT /id="PRO_0000290368"
FT DNA_BIND 96..152
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 188..245
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 39594 MW; 7EFD0BC829964967 CRC64;
MWNLNDSPDH HEESDSRGNP VGHVSNGMSQ SATWLPFVLP VTRNFFPAQS MEPGVRWSGF
NSVGKSDPSG SGRPEEPEIS PPIKKSRRGP RSRSSQYRGV TFYRRTGRWE SHIWDCGKQV
YLGGFDTAHA AARAYDRAAI KFRGVDADIN FDIEDYLDDL KQMGNLTKEE FMHVLRRQST
GFPRGSSKYR GVTLHKCGRW ESRLGQFLNK KYVYLGLFDT EIEAARAYDK AAIKCNGKDA
VTNFDPKVYE EEEDLSSETT RNGHNLGLSL GESSSEEFRL KSDIASIRSR IRDEERLLGS
DLSLAMMTTT VRSEKQQSDG GGNRVVGMAA SSGFSPQPSP YRIPRTFHFS RP
