ID   BTG_DICDI               Reviewed;         423 AA.
AC   Q54NU5;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=BTG family protein;
GN   Name=btg; ORFNames=DDB_G0285069;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the BTG family. {ECO:0000305}.
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DR   EMBL; AAFI02000073; EAL64998.1; -; Genomic_DNA.
DR   RefSeq; XP_639972.1; XM_634880.1.
DR   AlphaFoldDB; Q54NU5; -.
DR   SMR; Q54NU5; -.
DR   STRING; 44689.DDB0266860; -.
DR   PaxDb; Q54NU5; -.
DR   EnsemblProtists; EAL64998; EAL64998; DDB_G0285069.
DR   GeneID; 8624883; -.
DR   KEGG; ddi:DDB_G0285069; -.
DR   dictyBase; DDB_G0285069; btg.
DR   eggNOG; KOG4006; Eukaryota.
DR   HOGENOM; CLU_649614_0_0_1; -.
DR   InParanoid; Q54NU5; -.
DR   OMA; RAIICEE; -.
DR   Reactome; R-DDI-6804115; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain.
DR   PRO; PR:Q54NU5; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0045165; P:cell fate commitment; IGI:dictyBase.
DR   GO; GO:0008285; P:negative regulation of cell population proliferation; IBA:GO_Central.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IBA:GO_Central.
DR   Gene3D; 3.90.640.90; -; 1.
DR   InterPro; IPR002087; Anti_prolifrtn.
DR   InterPro; IPR033332; BTG.
DR   InterPro; IPR036054; BTG-like_sf.
DR   PANTHER; PTHR22978; PTHR22978; 1.
DR   Pfam; PF07742; BTG; 1.
DR   PRINTS; PR00310; ANTIPRLFBTG1.
DR   SMART; SM00099; btg1; 1.
DR   SUPFAM; SSF160696; SSF160696; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..423
FT                   /note="BTG family protein"
FT                   /id="PRO_0000344493"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          69..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          257..297
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          341..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  46423 MW;  E5150784FDFD04BD CRC64;
     MSPYAPENNQ DPGGGLVTEG NQPQQNNFVN TNKSPTTTPP PQTSNVVSTP PATAINAAGV
     NNGLINGVLN NSSSSSSSSS SSSSSSPTPT SISPPLSDIE QTLNAYPTDL PELVVAACWW
     AESLGKLNMN IPKENIKRFR KELIFALRDR IKGHWYPDYP ERGQGYRAII CEETTDRLLM
     DAAKKSDIVG EFRQLVKQNT TMWIDPGNVT YRHGKHYEKT LYPFNSINNH YSHHNNNNNN
     NNGINITNSN NTIPINTSGY HNINNHLNNS NNTIPPQQSQ QHINNNNNNS NNNTTNNIIL
     NSLHHHQTQI SQQHLNNNNN QNNFSYGITS TRLTQNVVNS NSNGLNGRVS SPSLSSTAPV
     FSPSNSMYHH VQQQSHSPSI SPPASPSKDL GNSSGNNTNV YSSNNNLFYN SNTSSSKIKL
     AYS