ID   TOLB2_NOVAD             Reviewed;         461 AA.
AC   Q2G9L1;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Tol-Pal system protein TolB 2 {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB2 {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=Saro_1017;
OS   Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG
OS   56034 / CIP 105152 / NBRC 16084 / F199).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=279238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 /
RC   F199;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N.,
RA   Fredrickson J., Balkwill D., Romine M.F., Richardson P.;
RT   "Complete sequence of Novosphingobium aromaticivorans DSM 12444.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000248; ABD25462.1; -; Genomic_DNA.
DR   RefSeq; WP_011444676.1; NC_007794.1.
DR   AlphaFoldDB; Q2G9L1; -.
DR   SMR; Q2G9L1; -.
DR   STRING; 279238.Saro_1017; -.
DR   EnsemblBacteria; ABD25462; ABD25462; Saro_1017.
DR   KEGG; nar:Saro_1017; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_5; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000009134; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           21..461
FT                   /note="Tol-Pal system protein TolB 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_0000259064"
FT   REGION          28..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   461 AA;  49703 MW;  879011104C91DD8B CRC64;
     MKIRHLLLLA GLVSAPAIVA AQQTALPSSS AAQASGDDDG GLTGSVSDES EWQDLGIAIP
     SFPTNASVPT AAEGGTTEAL GRNVARVVFN DLKNNGLFKP VGPDALPAIA FPQVAAPAFD
     AWRGRSAEML VQGFVKANED GRLTVGCYLY DVALGSELAR QGYVVKPEEW RRAAHKCADM
     VYSRLSGESP FFDSKIAYIA ETGPKDRRRK QLAIMDSDGA NHRFITNGQA TALTPRYSPD
     YSQIVYLSYL NGAPRIYIYN IGTGQQKLVT SSTNPTFAPR WSPDGKWILY SMSVAGNTDI
     YRVSVNGGAS TRLTDSPGID VGGSYSPDGS RIVFESDRSG SQQLYVMNAD GSNQKRISFF
     GGRAATPEWS PRGDQIAFTH LGGNFRIAVT DPSGGNMRFL TDSWQDEAPT WSPNGRIVQF
     FRTERGSGKT GIWQVDLTGR NERKLNTPVD GSDPAWGPVL P