ID   TOLB_ACTP2              Reviewed;         426 AA.
AC   A3MZ21;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=APL_0303;
OS   Actinobacillus pleuropneumoniae serotype 5b (strain L20).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=416269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L20;
RX   PubMed=18065534; DOI=10.1128/jb.01845-07;
RA   Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M.,
RA   Nash J.H.E.;
RT   "The complete genome sequence of Actinobacillus pleuropneumoniae L20
RT   (serotype 5b).";
RL   J. Bacteriol. 190:1495-1496(2008).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000569; ABN73407.1; -; Genomic_DNA.
DR   RefSeq; WP_005596216.1; NC_009053.1.
DR   AlphaFoldDB; A3MZ21; -.
DR   SMR; A3MZ21; -.
DR   STRING; 416269.APL_0303; -.
DR   EnsemblBacteria; ABN73407; ABN73407; APL_0303.
DR   GeneID; 66259151; -.
DR   KEGG; apl:APL_0303; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   Proteomes; UP000001432; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 4.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           25..426
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000026698"
SQ   SEQUENCE   426 AA;  44795 MW;  CA92B3993907B70E CRC64;
     MKLKSRFTSI IGVITLFFSQ TVTAESDVVI SVDEGVSMAQ PIAVVPFKAN GGVPADVGQI
     IADDLRNSGK FTPVERSKLP AQPGSAAEVN SQQWTDIGVD SVVVGQVTPT GGGYNVAYQL
     VDTLSNPATV LAQGAFNVPA AQIRQGAHTV SDQVFEKITQ IRGAFRTKIA YVVQRGVSSY
     ELRVSDYDGY NAFTVVKSKE PLMSPEWSPD GSRLAYVTFE NKKAQVVVHD LRSGSRRVVA
     ALRGHNGAPA FSPDGSRIAF ASNQDGELDI YVVGANGGKP SKLTANAGNN TEPSWSPDGS
     TIYFTSDRAG SPQVYRMGSS GGGASPMGGS GSYNAKVSSD GKNLIMIAGD KVVKRDLASG
     GTEVLSSTFL DESPSISPNG IMVIYSSTKG TSKVLQLVSA DGRFKANLPG AGGQFKFPAW
     SPYLTK