TOLB_ACTPJ
ID TOLB_ACTPJ Reviewed; 426 AA.
AC B0BT52;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=APJL_0316;
OS Actinobacillus pleuropneumoniae serotype 3 (strain JL03).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=434271;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JL03;
RX PubMed=18197260; DOI=10.1371/journal.pone.0001450;
RA Xu Z., Zhou Y., Li L., Zhou R., Xiao S., Wan Y., Zhang S., Wang K., Li W.,
RA Li L., Jin H., Kang M., Dalai B., Li T., Liu L., Cheng Y., Zhang L., Xu T.,
RA Zheng H., Pu S., Wang B., Gu W., Zhang X.L., Zhu G.-F., Wang S.,
RA Zhao G.-P., Chen H.;
RT "Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of
RT serotype 3 prevalent in China.";
RL PLoS ONE 3:E1450-E1450(2008).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC Rule:MF_00671}.
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DR EMBL; CP000687; ABY68909.1; -; Genomic_DNA.
DR RefSeq; WP_012262771.1; NC_010278.1.
DR AlphaFoldDB; B0BT52; -.
DR SMR; B0BT52; -.
DR EnsemblBacteria; ABY68909; ABY68909; APJL_0316.
DR KEGG; apj:APJL_0316; -.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OMA; VREPSWG; -.
DR OrthoDB; 821953at2; -.
DR Proteomes; UP000008547; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Periplasm; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT CHAIN 25..426
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT /id="PRO_1000131515"
SQ SEQUENCE 426 AA; 44821 MW; 1C5EC250088D9FAC CRC64;
MKLKSRFTSI IGVITLFFSQ TVTAESDVVI SVDEGVSMAQ PIAVVPFKAN GGVPADVGQI
IADDLRNSGK FTPVERSKLP AQPGSAAEVN SQQWTDIGVD SVVVGQVTPT GGGYNVAYQL
VDTLSNPATV LAQGAFNVPA AQIRQGAHTV SDQVFEKITQ IRGAFRTKIA YVVQRGVSSY
ELRVSDYDGY NAFTVVKSKE PLMSPEWSPD GSRLAYVTFE NKKAQVVVHD LRSGSRRVVA
ALRGHNGAPA FSPDGSRIAF ASNQDGELDI YVVGANGGKP SKLTANAGNN TEPSWSPDGS
TIYFTSDRAG SPQVYRMGLS GGGASPMGGS GSYNAKVSSD GKNLIMIAGD KVVKRDLASG
GTEVLSSTFL DESPSISPNG IMVIYSSTKG TSKVLQLVSA DGRFKANLPG AGGQFKFPAW
SPYLTK