ID   TOLB_AERS4              Reviewed;         441 AA.
AC   A4SJ35;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Tol-Pal system protein TolB {ECO:0000255|HAMAP-Rule:MF_00671};
DE   Flags: Precursor;
GN   Name=tolB {ECO:0000255|HAMAP-Rule:MF_00671}; OrderedLocusNames=ASA_0745;
OS   Aeromonas salmonicida (strain A449).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=382245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A449;
RX   PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA   Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA   Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA   Brown L.L.;
RT   "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT   the evolution of a fish pathogen.";
RL   BMC Genomics 9:427-427(2008).
CC   -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC       membrane invagination during cell division and is important for
CC       maintaining outer membrane integrity. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
CC   -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC       inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC       TolB and the outer membrane protein Pal. They form a network linking
CC       the inner and outer membranes and the peptidoglycan layer.
CC       {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00671}.
CC   -!- SIMILARITY: Belongs to the TolB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00671}.
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DR   EMBL; CP000644; ABO88907.1; -; Genomic_DNA.
DR   RefSeq; WP_011898362.1; NC_009348.1.
DR   AlphaFoldDB; A4SJ35; -.
DR   SMR; A4SJ35; -.
DR   STRING; 382245.ASA_0745; -.
DR   EnsemblBacteria; ABO88907; ABO88907; ASA_0745.
DR   GeneID; 60849677; -.
DR   KEGG; asa:ASA_0745; -.
DR   eggNOG; COG0823; Bacteria.
DR   HOGENOM; CLU_047123_0_0_6; -.
DR   OMA; VREPSWG; -.
DR   OrthoDB; 821953at2; -.
DR   Proteomes; UP000000225; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0017038; P:protein import; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 1.
DR   HAMAP; MF_00671; TolB; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR011659; PD40.
DR   InterPro; IPR014167; Tol-Pal_TolB.
DR   InterPro; IPR007195; TolB_N.
DR   Pfam; PF07676; PD40; 3.
DR   Pfam; PF04052; TolB_N; 1.
DR   TIGRFAMs; TIGR02800; propeller_TolB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Periplasm; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT   CHAIN           22..441
FT                   /note="Tol-Pal system protein TolB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00671"
FT                   /id="PRO_1000061935"
SQ   SEQUENCE   441 AA;  48182 MW;  1A45079AF05CB9D6 CRC64;
     MIRKVFFALV GCLLLSQSAQ AALDIVITGG IDSARPIAIA PFKWEGNGQL PQDIAEVVSN
     DLMRSGKFKP LARGQMPQTP SSSGEINFAP WASQGVEAVV VGSIAAVGDG TYKINFELVD
     VLKGQLAKTQ GGESNGYILD SRMATIPGAQ MRQFAHRISD IVYERLTGER GAFLTRIAYV
     SIEQGAQFPY QLRISDYDGY NEKTLLRSRE PLMSPAWSPD GSKLAYVSFE NQKSEIYVQD
     IYNQQRSLIS SFRGINGAPK WSPDGRRLAI VLSKDGQPDI YVIDVASKQL TRVTNTRVID
     TEPAWMPDGQ TLIFTSERGG KPQIYSVNLA TGVTRRMTWE GESNQGASVT PDGKSMVMVT
     RVQGQYRIAR QDMESGAMLV LTQSALDESP SVAPNGSMII YATIYQGRKS LALVSTDGRF
     KAVLPTSSGE IRAPAWSPFL N